Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.64 |
| ▸ | CA2 | P00918 | 1/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | KIT | P10721 | 1/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CDK2 | P24941 | 2/20 | 0.57 |
| ▸ | CDK1 | P06493 | 1/20 | 0.57 |
| ▸ | CDK4 | P11802 | 1/20 | 0.57 |
| ▸ | CDK7 | P50613 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13454714 | 0.89 | ALDH1A1 (0.79) | ALDH1A1RAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL10390737 | 0.86 | RAB9A (0.76) | ALDH1A1RAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL6300537 | 0.86 | RAB9A (0.75) | ALDH1A1RAB9ANPC1GAAMAPT | |
| SCHEMBL14096549 | 0.85 | RAB9A (0.74) | ALDH1A1RAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL14096418 | 0.85 | ALDH1A1 (0.81) | ALDH1A1RAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL11316756 | 0.84 | TDP1 (0.78) | ALDH1A1RAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL14096398 | 0.83 | RAB9A (0.70) | ALDH1A1RAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL5444566 | 0.82 | ALDH1A1 (0.69) | ALDH1A1RAB9ASMN1; SMN2NPC1GAA | |
| Hydrochloric Acid SCHEMBL3724619 | 0.81 | ALDH1A1 (0.75) | ALDH1A1RAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL14096442 | 0.81 | EPHX1 (0.76) | ALDH1A1RAB9ASMN1; SMN2NPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | ACHILLION PHARMACEUTICALS, INC. (US) | 2008-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207760-A1 | Pharmaceutical Compositions For and Methods of Inhibiting Hcv | RNASE1, SARS1, EIF2AK2 | ALDH1A1 2930/4885RAB9A 3144/4885SMN1; SMN2 4344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.