Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.75 |
| ▸ | NPC1 | O15118 | 4/20 | 0.70 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.68 |
| ▸ | TOP1 | P11387 | 1/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.68 |
| ▸ | METAP2 | P50579 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | PNLIP | P16233 | 1/20 | 0.65 |
| ▸ | SMO | Q99835 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.61 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.61 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10390737 | 0.88 | RAB9A (0.76) | RAB9AALDH1A1NPC1MT-CO2TOP1 | |
| SCHEMBL28603807 | 0.86 | KMT2A (0.66) | RAB9AALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL29891480 | 0.86 | KMT2A (0.66) | RAB9AALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL14096331 | 0.86 | ALDH1A1 (1.00) | RAB9AALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL15164883 | 0.86 | HTT (0.74) | RAB9AALDH1A1NPC1MT-CO2TOP1 | |
| SCHEMBL14228290 | 0.84 | SMO (0.65) | RAB9AALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL11590385 | 0.84 | KMT2A (0.83) | RAB9AALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL15164880 | 0.84 | PNLIP (0.72) | RAB9AALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL15164875 | 0.83 | PNLIP (0.76) | RAB9AALDH1A1NPC1KMT2AMEN1 | |
| SCHEMBL5080078 | 0.83 | PNLIP (0.91) | RAB9AALDH1A1NPC1METAP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897316-B2 | Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents | CHINA MEDICAL UNIVERSITY (TW) | 2005-05-24 | — | — | US | disclosed |
| US-20050032832-A1 | Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents | CHINA MEDICAL UNIVERSITY (TW) | 2005-02-10 | — | — | US | disclosed |
| US-4123554-A | Fungicidal and germicidal benzanilides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1978-10-31 | — | — | US | disclosed |
| US-3985804-A | Agricultural substituted 2-methylbenzanilide germicide | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) | 1976-10-12 | — | — | US | disclosed |
| US-3937840-A | COMPOSITIONS AND METHODS OF COMBATTING BACTERIA AND FUNGI USING 2-METHYLBENZANILIDE DERIVATIVES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JA) | 1976-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032832-A1 | Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents | TP53, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CHUK | RAB9A 1223/4885ALDH1A1 465/4885NPC1 1739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.