Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14098195 | 0.86 | SLC28A3 (0.37) | CTSBPTGS2CALM1MAPKAPK2SLC28A3 | |
| SCHEMBL14098220 | 0.84 | CALM1 (0.38) | CALM1SLC28A3 | |
| SCHEMBL5100866 | 0.83 | PTGS2 (0.42) | PTGS2 | |
| SCHEMBL14098102 | 0.82 | MAPKAPK2 (0.36) | PTGS2MAPKAPK2 | |
| SCHEMBL7115337 | 0.79 | AKR1B1 (0.47) | — | |
| SCHEMBL5107101 | 0.74 | AHR (0.39) | PTGS2MAPKAPK2 | |
| SCHEMBL7116087 | 0.74 | SMN1; SMN2 (0.42) | PTGS2MAPKAPK2 | |
| SCHEMBL7111884 | 0.74 | MAPKAPK2 (0.35) | PTGS2MAPKAPK2 | |
| SCHEMBL7112263 | 0.74 | AHR (0.39) | PTGS2MAPKAPK2 | |
| SCHEMBL14098209 | 0.73 | CALM1 (0.38) | CALM1SLC28A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7410997-B2 | Tricyclic fused heterocycle compounds, process for preparing the same and use thereof | NIPPON SULSAN KAISHA, LTD. (JP) | 2008-08-12 | — | — | US | disclosed |
| US-7410997-B2 | Tricyclic fused heterocycle compounds, process for preparing the same and use thereof | NIPPON SULSAN KAISHA, LTD. (JP) | 2008-08-12 | — | — | US | disclosed |