Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14098102 | 0.83 | MAPKAPK2 (0.36) | GAALMNAHPGDHSD17B10ALDH1A1 | |
| SCHEMBL14098220 | 0.82 | CALM1 (0.38) | GAAMAPTALOX15 | |
| SCHEMBL14098195 | 0.80 | SLC28A3 (0.37) | GAALMNAHPGDHSD17B10KDM4E | |
| SCHEMBL14098202 | 0.79 | CTSB (0.33) | — | |
| SCHEMBL11167585 | 0.78 | AKR1B1 (0.49) | AKR1B1GAALMNAHPGDHSD17B10 | |
| SCHEMBL14098262 | 0.77 | RAB9A (0.44) | GAALMNATDP1MAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL11659437 | 0.77 | AKR1B1 (0.48) | AKR1B1GAALMNAHPGDHSD17B10 | |
| SCHEMBL5100866 | 0.77 | PTGS2 (0.42) | LMNAHSD17B10TSHRTDP1KDM4E | |
| SCHEMBL7117535 | 0.76 | HSD17B1 (0.41) | HPGDKDM4EPOLBMAPTAPEX1 | |
| SCHEMBL5112413 | 0.76 | ATM (0.45) | HPGDMAPTALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065021-A1 | Tracheal smooth muscle relaxants | YAMASHITA SHINYA (JP) | 2003-04-03 | — | — | US | disclosed |
| US-6495592-B1 | DIBENZ(B,F)OXEPIN DERIVATIVES; ANTIASTHMATICS | NIPPON SUISAN KAISHA, LTD. (JP) | 2002-12-17 | — | — | US | disclosed |
| US-6180659-B1 | USING A DIBENZO(B,F)-(OXEPIN OR THIEPIN) COMPOUND | NIPPON SUISAN KAISHA, LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-0885610-A1 | TRACHEAL SMOOTH MUSCLE RELAXANT | NIPPON SUISAN KAISHA, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065021-A1 | Tracheal smooth muscle relaxants | MYLK, MUSK, CPT1B | AKR1B1 331/4885GAA 4581/4885LMNA 1131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.