Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A11 | P48066 | 4/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14355199 | 0.89 | SLC6A11 (0.43) | SLC6A11SLC6A1HDAC1KMT2AKIF11 | |
| SCHEMBL887529 | 0.86 | SLC6A11 (0.44) | SLC6A11SLC6A1KMT2AKIF11MEN1 | |
| SCHEMBL12824151 | 0.81 | SLC6A11 (0.41) | SLC6A11SLC6A1KMT2AKIF11MEN1 | |
| SCHEMBL12004703 | 0.77 | PDE4B (0.51) | SLC6A11SLC6A1KMT2AKIF11MEN1 | |
| SCHEMBL12005099 | 0.77 | PDE4B (0.51) | SLC6A11SLC6A1KMT2AKIF11MEN1 | |
| SCHEMBL12004675 | 0.77 | PDE4B (0.51) | SLC6A11SLC6A1KMT2AKIF11MEN1 | |
| SCHEMBL28577719 | 0.76 | PDE4B (0.52) | SLC6A11SLC6A1KMT2AKIF11MEN1 | |
| SCHEMBL13551201 | 0.75 | GAA (0.48) | SLC6A11SLC6A1HDAC6GAAKMT2A | |
| SCHEMBL19895670 | 0.75 | HPGD (0.46) | SLC6A11SLC6A1HDAC6GAAKMT2A | |
| SCHEMBL4428713 | 0.74 | SLC6A11 (0.44) | SLC6A11SLC6A1KMT2AKIF11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080182980-A1 | Reactive Functional Groups | THIRD WAVE TECHNOLOGIES, INC. (US) | 2008-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182980-A1 | Reactive Functional Groups | POLRMT, RNGTT, APEX1 | SLC6A11 4693/4885SLC6A1 4721/4885HDAC6 2020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.