SCHEMBL887529

SCHEMBL887529

COc1ccc(C(OCCCCCC(OC(C)=O)C(CCCO)OC(C)=O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SLC6A11 P48066 7/20 0.44
SLC6A1 P30531 3/20 0.44
KIF11 P52732 6/20 0.41
SLC6A12 P48065 2/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
KMT2A Q03164 1/20 0.39
SLC6A13 Q9NSD5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12824151 0.94 SLC6A11 (0.41) SLC6A11SLC6A1KIF11SLC6A12MEN1
SCHEMBL14355199 0.91 SLC6A11 (0.43) SLC6A11SLC6A1KIF11SLC6A12MEN1
SCHEMBL14099533 0.86 SLC6A11 (0.40) SLC6A11SLC6A1KIF11SLC6A12MEN1
SCHEMBL13867925 0.85 SLC6A11 (0.41) SLC6A11SLC6A1KIF11SLC6A12MEN1
SCHEMBL2631346 0.84 SLC6A11 (0.43) SLC6A11SLC6A1KIF11SLC6A12MEN1
SCHEMBL6849984 0.83 SLC6A11 (0.46) SLC6A11SLC6A1KIF11SLC6A12MEN1
SCHEMBL887485 0.83 SLC6A11 (0.46) SLC6A11SLC6A1KIF11SLC6A12MEN1
SCHEMBL27051202 0.83 SLC6A11 (0.46) SLC6A11SLC6A1KIF11SLC6A12MEN1
SCHEMBL1260569 0.83 SLC6A11 (0.46) SLC6A11SLC6A1KIF11SLC6A12MEN1
SCHEMBL13427508 0.83 SLC6A11 (0.46) SLC6A11SLC6A1KIF11SLC6A12MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9999866-B2 Preparation of templates for nucleic acid sequencing ILLUMINA CAMBRIDGE LIMITED (GB) 2018-06-19 US disclosed
US-20170145499-A1 METHODS FOR INDEXING SAMPLES AND SEQUENCING MULTIPLE POLYNUCLEOTIDE TEMPLATES ILLUMINA CAMBRIDGE LIMITED (US) 2017-05-25 US disclosed
US-20170021325-A1 Preparation of Templates for Nucleic Acid Sequencing SOLEXA LIMITED (GB) 2017-01-26 US disclosed
US-20170021325-A1 Preparation of Templates for Nucleic Acid Sequencing SOLEXA LIMITED (GB) 2017-01-26 US disclosed
US-9512478-B2 Methods for indexing samples and sequencing multiple polynucleotide templates ILLUMINA CAMBRIDGE LIMITED (GB) 2016-12-06 US disclosed
US-9512478-B2 Methods for indexing samples and sequencing multiple polynucleotide templates ILLUMINA CAMBRIDGE LIMITED (GB) 2016-12-06 US disclosed
US-9498763-B2 Preparation of templates for nucleic acid sequencing ILLUMINA CAMBRIDGE LIMITED (GB) 2016-11-22 US disclosed
US-9498763-B2 Preparation of templates for nucleic acid sequencing ILLUMINA CAMBRIDGE LIMITED (GB) 2016-11-22 US disclosed
US-20160090623-A1 METHOD FOR PAIRWISE SEQUENCING OF TARGET POLYNUCLEOTIDES ILLUMINA CAMBRIDGE LIMITED (GB) 2016-03-31 US disclosed
US-20160090623-A1 METHOD FOR PAIRWISE SEQUENCING OF TARGET POLYNUCLEOTIDES ILLUMINA CAMBRIDGE LIMITED (GB) 2016-03-31 US disclosed
US-7754429-B2 Method for pair-wise sequencing a plurity of target polynucleotides ILLUMINA CAMBRIDGE LIMITED (GB) 2010-07-13 US disclosed
US-7754429-B2 Method for pair-wise sequencing a plurity of target polynucleotides ILLUMINA CAMBRIDGE LIMITED (GB) 2010-07-13 US disclosed
US-20090233802-A1 Methods for indexing samples and sequencing multiple polynucleotide templates NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-09-17 US disclosed
US-20090233802-A1 Methods for indexing samples and sequencing multiple polynucleotide templates NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-09-17 US disclosed
US-20090118128-A1 Preparation of templates for nucleic acid sequencing ILLUMINA CAMBRIDGE LIMITED (GB) 2009-05-07 US disclosed
US-20090088327-A1 Method for sequencing a polynucleotide template SOLEXA LIMITED (GB) 2009-04-02 US disclosed
US-20090088327-A1 Method for sequencing a polynucleotide template SOLEXA LIMITED (GB) 2009-04-02 US disclosed
WO-2008093098-A2 METHODS FOR INDEXING SAMPLES AND SEQUENCING MULTIPLE NUCLEOTIDE TEMPLATES ILLUMINA CAMBRIDGE LIMITED (GB) 2008-08-07 WO disclosed
WO-2008041002-A2 METHOD FOR SEQUENCING A POLYNUCLEOTIDE TEMPLATE ILLUMINA CAMBRIDGE LIMITED (GB) 2008-04-10 WO disclosed
WO-2007010251-A2 PREPARATION OF TEMPLATES FOR NUCLEIC ACID SEQUENCING SOLEXA LIMITED (GB) 2007-01-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090118128-A1 Preparation of templates for nucleic acid sequencing RNGTT, POLRMT, POLM SLC6A11 4807/4885SLC6A1 4778/4885KIF11 1305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.