SCHEMBL14099591

SCHEMBL14099591

Cc1c2ccc(Br)cc2c(C)c2ccc(Br)cc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.42
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 2/20 0.40
KIT P10721 1/20 0.38
CYP2A6 P11509 2/20 0.37
JAK2 O60674 3/20 0.37
METAP2 P50579 1/20 0.37
CHEK1 O14757 1/20 0.37
AURKA O14965 1/20 0.37
DAPK3 O43293 1/20 0.37
PRKD3 O94806 1/20 0.37
MAP4K4 O95819 1/20 0.37
PAK4 O96013 1/20 0.37
ABL1 P00519 1/20 0.37
NTRK1 P04629 1/20 0.37
CSF1R P07333 1/20 0.37
RET P07949 1/20 0.37
MET P08581 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19713318 0.93 MAPK1 (0.43) ESR2ALDH1A1LMNAHPGDMAPK1
SCHEMBL3744740 0.89 ESR2 (0.42) ESR2ALDH1A1LMNAHPGDMAPK1
SCHEMBL57643 0.89 ESR2 (0.46) ESR2ALDH1A1LMNAHPGDMAPK1
SCHEMBL19757717 0.85 ESR2 (0.41) ESR2ALDH1A1LMNAHPGDMAPK1
SCHEMBL28583244 0.80 KMT2A (0.44) ESR2ALDH1A1LMNAHPGDMAPK1
SCHEMBL28276718 0.80 ALDH1A1 (0.46) ESR2ALDH1A1LMNAHPGDMAPK1
SCHEMBL20313052 0.80 KIF11 (0.44) ESR2ALDH1A1LMNAHPGDCYP2A6
SCHEMBL38662570 0.79 CYP2A6 (0.42) ESR2ALDH1A1LMNAHPGDMAPK1
SCHEMBL20313054 0.79 S100B (0.47) ALDH1A1LMNAHPGDMAPK1CYP1A2
SCHEMBL8781298 0.78 HSD17B10 (0.73) ALDH1A1HPGDMAPK1CYP2A6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9620721-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-11 US disclosed
US-8795855-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2014-08-05 US disclosed
US-20140151676-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2014-06-05 US disclosed
US-20080182129-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC 2008-07-31 US disclosed