Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 3/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19757717 | 0.91 | ESR2 (0.41) | ESR2ALDH1A1LMNAHPGDMAPK1 | |
| SCHEMBL28276718 | 0.91 | ALDH1A1 (0.46) | ESR2ALDH1A1LMNAHPGDMAPK1 | |
| SCHEMBL14099591 | 0.89 | ESR2 (0.42) | ESR2ALDH1A1LMNAHPGDMAPK1 | |
| SCHEMBL3744740 | 0.89 | ESR2 (0.42) | ESR2ALDH1A1LMNAHPGDMAPK1 | |
| SCHEMBL28583244 | 0.85 | KMT2A (0.44) | ESR2ALDH1A1LMNAHPGDMAPK1 | |
| SCHEMBL19713318 | 0.82 | MAPK1 (0.43) | ESR2ALDH1A1LMNAHPGDMAPK1 | |
| SCHEMBL16158369 | 0.82 | CYP2A6 (0.47) | ESR2ALDH1A1MAPK1KMT2ACYP2A6 | |
| SCHEMBL28583249 | 0.79 | ALDH1A1 (0.47) | ESR2ALDH1A1MAPK1KMT2AJAK2 | |
| SCHEMBL18481324 | 0.77 | ALDH1A1 (0.50) | ESR2ALDH1A1KMT2AAURKAKDR | |
| SCHEMBL13616030 | 0.77 | BCL2 (0.45) | ESR2ALDH1A1MAPK1KMT2ACYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287506-B1 | PHENANTHRENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2020-02-26 | — | — | EP | disclosed |
| EP-1797158-B1 | PHENANTHRENE DERIVATIVES | MERCK PATENT GMBH (DE) | 2019-05-01 | — | — | EP | disclosed |
| US-9966534-B2 | Polymer and device | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2018-05-08 | — | — | US | disclosed |
| EP-3287506-A1 | PHENANTHRENE DERIVATIVES | Merck Patent GmbH (DE) | 2018-02-28 | — | — | EP | disclosed |
| US-20150333262-A1 | POLYMER AND DEVICE | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2015-11-19 | — | — | US | disclosed |
| US-8129037-B2 | Phenanthrene derivative | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-7947382-B2 | Electroluminescent polymers and the use thereof | MERCK PATENT GMBH (DE) | 2011-05-24 | — | — | US | disclosed |
| US-7947382-B2 | Electroluminescent polymers and the use thereof | MERCK PATENT GMBH (DE) | 2011-05-24 | — | — | US | disclosed |
| US-7947382-B2 | Electroluminescent polymers and the use thereof | MERCK PATENT GMBH (DE) | 2011-05-24 | — | — | US | disclosed |
| US-20090026919-A1 | PHENANTHRENE DERIVATIVE | MERCK PATEN GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2009-01-29 | — | — | US | disclosed |
| EP-1741149-B1 | ELECTROLUMINESCENT POLYMERS AND USE THEROF | MERCK PATENT GMBH (DE) | 2008-12-24 | — | — | EP | disclosed |
| EP-1741149-B1 | ELECTROLUMINESCENT POLYMERS AND USE THEROF | MERCK PATENT GMBH (DE) | 2008-12-24 | — | — | EP | disclosed |
| US-20070205714-A1 | Electroluminescent Polymers and the Use Thereof | MERCK PATENT GMBH (DE) | 2007-09-06 | — | — | US | disclosed |
| US-20070205714-A1 | Electroluminescent Polymers and the Use Thereof | MERCK PATENT GMBH (DE) | 2007-09-06 | — | — | US | disclosed |
| US-20070205714-A1 | Electroluminescent Polymers and the Use Thereof | MERCK PATENT GMBH (DE) | 2007-09-06 | — | — | US | disclosed |
| EP-1797158-A1 | PHENANTHRENE DERIVATIVE | Merck Patent GmbH (DE) | 2007-06-20 | — | — | EP | disclosed |
| EP-1741149-A1 | ELECTROLUMINESCENT POLYMERS AND USE THEROF | MERCK PATENT GmbH (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2006039982-A1 | PHENANTHRENE DERIVATIVE | MERCK PATENT GMBH (DE) | 2006-04-20 | — | — | WO | disclosed |
| EP-1645610-A1 | Phenanthrene derivatives | Covion Organic Semiconductors GmbH (DE) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005104264-A1 | ELECTROLUMINESCENT POLYMERS AND USE THEROF | MERCK PATENT GMBH (DE) | 2005-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090026919-A1 | PHENANTHRENE DERIVATIVE | LEF1, CRY1, WNT1 | ESR2 113/4885ALDH1A1 262/4885LMNA 1767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.