Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444099 | 0.88 | ALDH1A1 (0.50) | ALDH1A1CYP1A2HSD17B10HPGDTHRB | |
| SCHEMBL30744773 | 0.84 | HSD17B10 (0.58) | ALDH1A1CYP1A2HSD17B10HPGDTHRB | |
| SCHEMBL3786972 | 0.84 | HSD17B10 (0.58) | ALDH1A1CYP1A2HSD17B10HPGDTHRB | |
| SCHEMBL3792057 | 0.84 | HSD17B10 (0.58) | ALDH1A1CYP1A2HSD17B10HPGDTHRB | |
| SCHEMBL441488 | 0.82 | HSD17B10 (0.56) | ALDH1A1CYP1A2HSD17B10HPGDTHRB | |
| SCHEMBL31529058 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CYP1A2HSD17B10HPGDTHRB | |
| SCHEMBL442152 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CYP1A2HSD17B10HPGDTHRB | |
| SCHEMBL2081468 | 0.78 | ALDH1A1 (0.50) | ALDH1A1CYP1A2HSD17B10HPGDTHRB | |
| SCHEMBL444017 | 0.77 | ALDH1A1 (0.60) | ALDH1A1CYP1A2HSD17B10HPGDTHRB | |
| SCHEMBL6900684 | 0.77 | ALDH1A1 (0.44) | ALDH1A1CYP1A2HSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080166593-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
| US-20080166593-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080166593-A1 | Organic Electroluminescent Devices | OR10J3, DDT, EML4 | ALDH1A1 610/4885CYP1A2 870/4885HSD17B10 2215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.