SCHEMBL442152

SCHEMBL442152

c1cc2ccc3ccc(Oc4ccc5ccc6cccc7ccc4c5c67)c4ccc(c1)c2c34

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
HPGD P15428 5/20 0.52
HSD17B10 Q99714 4/20 0.52
CYP1A2 P05177 4/20 0.52
CYP3A4 P08684 3/20 0.52
TSHR P16473 3/20 0.52
CYP1A1 P04798 2/20 0.52
CYP1B1 Q16678 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
ERBB2 P04626 1/20 0.48
FYN P06241 1/20 0.48
MAOA P21397 1/20 0.48
ACHE P22303 1/20 0.48
AHR P35869 1/20 0.48
THRB P10828 1/20 0.48
KMT2A Q03164 4/20 0.42
MEN1 O00255 2/20 0.42
KDM4E B2RXH2 4/20 0.40
MAPT P10636 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31529058 1.00 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10CYP1A2CYP3A4
SCHEMBL444099 0.90 ALDH1A1 (0.50) ALDH1A1HPGDHSD17B10CYP1A2CYP3A4
SCHEMBL443084 0.86 CYP1A2 (0.46) ALDH1A1HPGDHSD17B10CYP1A2CYP3A4
SCHEMBL27589979 0.84 ALDH1A1 (0.46) ALDH1A1HPGDHSD17B10CYP1A2CYP3A4
SCHEMBL15428349 0.82 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10CYP1A2CYP3A4
SCHEMBL2351815 0.82 HPGD (0.54) ALDH1A1HPGDHSD17B10CYP1A2CYP3A4
SCHEMBL717395 0.80 ALDH1A1 (0.47) ALDH1A1HPGDHSD17B10CYP1A2CYP3A4
SCHEMBL276464 0.79 HPGD (0.39) ALDH1A1HPGDHSD17B10CYP1A2CYP3A4
SCHEMBL27786585 0.79 ALDH1A1 (0.45) ALDH1A1HPGDHSD17B10CYP1A2CYP3A4
SCHEMBL14101036 0.78 ALDH1A1 (0.42) ALDH1A1HPGDHSD17B10CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8846846-B2 Naphthalene derivative, resist bottom layer material, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-09-30 US claimed
US-20120064725-A1 NAPHTHALENE DERIVATIVE, RESIST BOTTOM LAYER MATERIAL, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-15 US claimed
US-9045587-B2 Naphthalene derivative, resist bottom layer material, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-06-02 US disclosed
US-20140363768-A1 NAPHTHALENE DERIVATIVE, RESIST BOTTOM LAYER MATERIAL, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-12-11 US disclosed
US-8846846-B2 Naphthalene derivative, resist bottom layer material, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2014-09-30 US disclosed
US-20120064725-A1 NAPHTHALENE DERIVATIVE, RESIST BOTTOM LAYER MATERIAL, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-15 US disclosed
WO-2011018355-A1 PRESSURE-SENSITIVE PAINT Deutsches Zentrum für Luft- und Raumfahrt e.V. (DE) 2011-02-17 WO disclosed