Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.32 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26943690 | 0.74 | GRIN1 (0.33) | — | |
| SCHEMBL466252 | 0.73 | FKBP5 (0.37) | FKBP5CRBN | |
| SCHEMBL14140547 | 0.69 | CCR2 (0.38) | FKBP5CRBN | |
| SCHEMBL11723152 | 0.69 | FKBP5 (0.37) | FKBP5CRBN | |
| SCHEMBL9129408 | 0.68 | CRBN (0.40) | FKBP5CRBN | |
| SCHEMBL11316947 | 0.66 | FKBP5 (0.39) | FKBP5CRBN | |
| SCHEMBL6673999 | 0.66 | FKBP5 (0.39) | FKBP5CRBN | |
| SCHEMBL23794084 | 0.65 | METAP2 (0.31) | — | |
| SCHEMBL23869976 | 0.65 | METAP2 (0.31) | — | |
| SCHEMBL28279697 | 0.65 | FKBP5 (0.35) | FKBP5CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414078-B2 | Oral general anesthetics and metabolitically resistant anticonvulsants | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-08-19 | — | — | US | disclosed |
| US-7414078-B2 | Oral general anesthetics and metabolitically resistant anticonvulsants | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-08-19 | — | — | US | disclosed |