Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172572 | 0.89 | S1PR3 (0.41) | ALDH1A1TRPM8CTSSCTSKMAPT | |
| SCHEMBL18683503 | 0.81 | CTSS (0.42) | ALDH1A1CTSSCTSKMAPTLMNA | |
| SCHEMBL3196849 | 0.77 | CTSK (0.39) | ALDH1A1TRPM8CTSSCTSKMAPT | |
| Lithium Ion SCHEMBL23200770 | 0.76 | S1PR3 (0.42) | TRPM8CTSSCTSKAAK1S1PR3 | |
| SCHEMBL4707517 | 0.76 | PPARA (0.44) | CTSSCTSKMAPTSCN9ASCN10A | |
| SCHEMBL24872366 | 0.75 | NPC1 (0.44) | ALDH1A1CTSSCTSKMAPTLMNA | |
| SCHEMBL6784979 | 0.75 | CTSK (0.49) | CTSSCTSKMAPTKLK5PPARG | |
| SCHEMBL12068193 | 0.75 | CTSK (0.49) | CTSSCTSKMAPTKLK5PPARG | |
| SCHEMBL12069800 | 0.75 | CTSK (0.49) | CTSSCTSKMAPTKLK5PPARG | |
| SCHEMBL4186308 | 0.74 | TRPM8 (0.39) | TRPM8MAPTLMNAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023053054-A1 | PROCESS FOR THE PREPARATION OF TAXANE DERIVATIVES | INDENA S.P.A. (IT) | 2023-04-06 | — | — | WO | disclosed |
| EP-1221445-B1 | PENTACYCLIC TAXANE COMPOUNDS | DAIICHI SANKYO CO LTD (JP) | 2008-08-20 | — | — | EP | disclosed |