Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101230 | 0.89 | ALDH1A1 (0.38) | S1PR3CTSSCTSKPTPN1TRPM8 | |
| SCHEMBL4186308 | 0.84 | TRPM8 (0.39) | TRPM8MAPTLMNAHPGDMAPK1 | |
| SCHEMBL3196849 | 0.82 | CTSK (0.39) | S1PR3CTSSCTSKPTPN1TRPM8 | |
| SCHEMBL4181986 | 0.81 | TRPA1 (0.39) | CTSSCTSKHSD17B10TRPA1PPARA | |
| SCHEMBL4707517 | 0.81 | PPARA (0.44) | CTSSCTSKPTPN1SCN9ACYP3A4 | |
| SCHEMBL4177618 | 0.80 | CTSS (0.46) | S1PR3CTSSCTSKPTPN1PPARA | |
| SCHEMBL4179051 | 0.79 | PPARA (0.40) | CTSSCTSKTRPA1PPARAPPARG | |
| Lithium Ion SCHEMBL23200770 | 0.77 | S1PR3 (0.42) | S1PR3CTSSCTSKPTPN1TRPM8 | |
| Acetone SCHEMBL2678521 | 0.76 | CTSK (0.49) | CTSSCTSKMAPTPPARAPPARG | |
| SCHEMBL7087412 | 0.75 | CTSK (0.51) | CTSSCTSKMAPTPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1887360-B1 | TEST METHOD FOR ENDOTOXIN | DAIICHI SANKYO CO LTD (JP) | 2015-04-08 | — | — | EP | claimed |
| US-7410980-B2 | Crystals of taxane derivative and process for their production | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-08-12 | — | — | US | claimed |
| EP-1457492-B1 | CRYSTALS OF TAXANE DERIVATIVE AND PROCESS FOR THEIR PRODUCTION | DAIICHI SANKYO CO LTD (JP) | 2008-01-02 | — | — | EP | claimed |
| EP-1457492-A1 | CRYSTALS OF TAXANE DERIVATIVE AND PROCESS FOR THEIR PRODUCTION | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-09-15 | — | — | EP | claimed |
| US-20090186868-A1 | Taxane Compound Having Azetidine Ring Structure | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-07-23 | — | — | US | disclosed |
| US-7456302-B2 | (1S,2S,3R,4S,5R,8R,9S,10R,13S)-4-Acetoxy-2-benzoyloxy-5,20-epoxy-1,13-dihydroxy-9,10-[(1S)-2-propenylidenedioxy]tax-6,11-diene; antitumor compounds; using low toxic and inexpensive materials; product is readily purified; industrial production | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-11-25 | — | — | US | disclosed |
| EP-1221445-B1 | PENTACYCLIC TAXANE COMPOUNDS | DAIICHI SANKYO CO LTD (JP) | 2008-08-20 | — | — | EP | disclosed |
| US-7410980-B2 | Crystals of taxane derivative and process for their production | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-08-12 | — | — | US | disclosed |
| US-7410980-B2 | Crystals of taxane derivative and process for their production | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2008-08-12 | — | — | US | disclosed |
| EP-1942109-A1 | TAXANE COMPOUND WITH AZETIDINE RING STRUCTURE | Daiichi Sankyo Company, Limited (JP) | 2008-07-09 | — | — | EP | disclosed |
| EP-1457492-B1 | CRYSTALS OF TAXANE DERIVATIVE AND PROCESS FOR THEIR PRODUCTION | DAIICHI SANKYO CO LTD (JP) | 2008-01-02 | — | — | EP | disclosed |
| US-20070167630-A1 | Method for producing pentacyclic taxans | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2007-07-19 | — | — | US | disclosed |
| US-20050070579-A1 | Crystals of taxane derivative and process for their production | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2005-03-31 | — | — | US | disclosed |
| US-20050070579-A1 | Crystals of taxane derivative and process for their production | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2005-03-31 | — | — | US | disclosed |
| EP-1457492-A1 | CRYSTALS OF TAXANE DERIVATIVE AND PROCESS FOR THEIR PRODUCTION | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-09-15 | — | — | EP | disclosed |
| EP-1457492-A1 | CRYSTALS OF TAXANE DERIVATIVE AND PROCESS FOR THEIR PRODUCTION | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-09-15 | — | — | EP | disclosed |
| US-6677456-B2 | AS ANTITUMOR COMPOUND; CAN BE ORALLY ADMINISTERED | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-01-13 | — | — | US | disclosed |
| WO-2003045953-A1 | CRYSTALS OF TAXANE DERIVATIVE AND PROCESS FOR THEIR PRODUCTION | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |
| US-20020143178-A1 | Pentacyclic taxan compound | DAIICHI PHARMACEUTICAL CO., LTD. | 2002-10-03 | — | — | US | disclosed |
| EP-1221445-A1 | PENTACYCLIC TAXANE COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2002-07-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070579-A1 | Crystals of taxane derivative and process for their production | TERT, NT5C, TXLNA | S1PR3 1216/4885CTSS 4536/4885CTSK 4309/4885 |
| US-20090186868-A1 | Taxane Compound Having Azetidine Ring Structure | ABCC1, AZI2, TPD52L2 | S1PR3 3187/4885CTSS 4449/4885CTSK 4401/4885 |
| US-20070167630-A1 | Method for producing pentacyclic taxans | DPYD, NCL, FOLR1 | S1PR3 1224/4885CTSS 3401/4885CTSK 2556/4885 |
| US-20020143178-A1 | Pentacyclic taxan compound | TUBB6, TUBB1, TUBA1A | S1PR3 106/4885CTSS 3840/4885CTSK 3228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.