Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL865129 | 0.88 | HSD11B1 (0.58) | HSD11B1ALDH1A1HPGDSMN1; SMN2EPHX2 | |
| SCHEMBL14100861 | 0.85 | HSD11B1 (0.51) | HSD11B1ALDH1A1HPGDSMN1; SMN2EPHX2 | |
| SCHEMBL30406939 | 0.81 | SMN1; SMN2 (0.45) | ALDH1A1HPGDSMN1; SMN2NPC1LMNA | |
| SCHEMBL4739829 | 0.79 | ALDH1A1 (0.59) | ALDH1A1HPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL16242079 | 0.79 | ALDH1A1 (0.55) | HSD11B1ALDH1A1HPGDSMN1; SMN2EPHX2 | |
| SCHEMBL18106018 | 0.78 | MAOB (0.51) | ALDH1A1HPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL18106023 | 0.78 | MAOB (0.51) | ALDH1A1HPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL18106021 | 0.78 | MAOB (0.51) | ALDH1A1HPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL1627925 | 0.78 | CYP4A11 (0.60) | ALDH1A1HPGDSMN1; SMN2NPC1CYP3A4 | |
| SCHEMBL18106024 | 0.78 | MAOB (0.51) | ALDH1A1HPGDSMN1; SMN2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008096093-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AND THEIR USES | ARGENTA DISCOVERY LTD. (GB) | 2008-08-14 | — | — | WO | disclosed |