Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CXCR3 | P49682 | 3/20 | 0.33 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4720070 | 0.91 | F10 (0.34) | F10F2ARCXCR3 | |
| SCHEMBL4720064 | 0.91 | F10 (0.34) | F10F2ARCXCR3 | |
| SCHEMBL14101712 | 0.90 | F10 (0.39) | F10F2CXCR3MAPTSLC16A3 | |
| SCHEMBL14101709 | 0.90 | F10 (0.39) | F10F2CXCR3MAPTSLC16A3 | |
| SCHEMBL4722372 | 0.90 | F10 (0.38) | F10F2CXCR3MAPTSLC16A3 | |
| SCHEMBL14101989 | 0.89 | ADRA1D (0.39) | SMN1; SMN2LMNAMEN1KMT2ATSHR | |
| SCHEMBL4724288 | 0.87 | F10 (0.40) | F10F2MAPTSLC16A3SLC16A1 | |
| SCHEMBL14101737 | 0.87 | CCR1 (0.39) | F10F2CYP2C19MAPT | |
| SCHEMBL4724067 | 0.84 | KMT2A (0.34) | F10F2CXCR3MEN1KMT2A | |
| SCHEMBL4724059 | 0.84 | KMT2A (0.34) | F10F2CXCR3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |