Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721931 | 0.89 | MAPT (0.36) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4720458 | 0.89 | MAPT (0.36) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4722264 | 0.87 | MAPT (0.47) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4721816 | 0.85 | MAPT (0.38) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4722053 | 0.85 | CTDSP1 (0.36) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4720984 | 0.85 | ALDH1A1 (0.36) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4722028 | 0.83 | MAPT (0.39) | MAPTALDH1A1LMNAPOLB | |
| SCHEMBL4720715 | 0.83 | MAPT (0.46) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4723560 | 0.82 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4723319 | 0.82 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |