Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4721931 | 0.95 | MAPT (0.36) | CTDSP1MAPTALDH1A1LMNAPOLB | |
| SCHEMBL4720984 | 0.91 | ALDH1A1 (0.36) | MAPTALDH1A1LMNAPOLBGAA | |
| SCHEMBL4720715 | 0.88 | MAPT (0.46) | MAPTALDH1A1LMNAPOLBGAA | |
| SCHEMBL4720458 | 0.86 | MAPT (0.36) | MAPTALDH1A1LMNAPOLBGAA | |
| SCHEMBL4719136 | 0.86 | MAPT (0.37) | MAPTALDH1A1LMNAPOLBSMN1; SMN2 | |
| SCHEMBL14101727 | 0.85 | MAPT (0.36) | MAPTALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL4722264 | 0.84 | MAPT (0.47) | MAPTALDH1A1LMNAPOLBGAA | |
| SCHEMBL4721273 | 0.84 | MAPT (0.37) | CTDSP1MAPTALDH1A1LMNAPOLB | |
| SCHEMBL4719649 | 0.84 | MEN1 (0.40) | CTDSP1MAPTALDH1A1LMNAPOLB | |
| SCHEMBL4721816 | 0.81 | MAPT (0.38) | MAPTALDH1A1LMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |