Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 4/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101733 | 0.91 | F10 (0.38) | ALDH1A1MAPTKDM4EGAAADORA1 | |
| SCHEMBL4722188 | 0.90 | P2RX7 (0.36) | P2RX7CXCR3NOTUM | |
| SCHEMBL4722181 | 0.90 | P2RX7 (0.36) | P2RX7CXCR3NOTUM | |
| SCHEMBL4724669 | 0.82 | MAPT (0.35) | ALDH1A1MAPTLMNAGAAP2RX7 | |
| SCHEMBL4718551 | 0.81 | P2RX7 (0.36) | MAPTKDM4EP2RX7CXCR3F2 | |
| SCHEMBL4718554 | 0.81 | P2RX7 (0.36) | MAPTKDM4EP2RX7CXCR3F2 | |
| SCHEMBL4720459 | 0.80 | F10 (0.40) | MAPTF2F10 | |
| SCHEMBL4718815 | 0.79 | TSHR (0.37) | ALDH1A1MAPTKDM4EADORA1POLB | |
| SCHEMBL4720117 | 0.78 | SMPD3 (0.38) | ALDH1A1KDM4EMAPK1 | |
| SCHEMBL4720123 | 0.78 | SMPD3 (0.38) | ALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |