Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.33 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14101734 | 0.91 | ALDH1A1 (0.35) | F10F2ALDH1A1GAAMAPT | |
| SCHEMBL4720459 | 0.90 | F10 (0.40) | F10F2MAPTSLC16A3SLC16A1 | |
| SCHEMBL4718554 | 0.90 | P2RX7 (0.36) | F10F2TSHRMAPTKDM4E | |
| SCHEMBL4718551 | 0.90 | P2RX7 (0.36) | F10F2TSHRMAPTKDM4E | |
| SCHEMBL4718815 | 0.89 | TSHR (0.37) | TSHRALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL4720123 | 0.87 | SMPD3 (0.38) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL4720117 | 0.87 | SMPD3 (0.38) | ALDH1A1KDM4EHPGDSMN1; SMN2MAPK1 | |
| SCHEMBL14101712 | 0.85 | F10 (0.39) | F10F2MAPTSLC16A3SLC16A1 | |
| SCHEMBL14101709 | 0.85 | F10 (0.39) | F10F2MAPTSLC16A3SLC16A1 | |
| SCHEMBL4724288 | 0.85 | F10 (0.40) | F10F2MAPTNPSR1SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |