Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722057 | 0.91 | GRIN2B (0.35) | KCNK3THRBGRIN2BP2RX7GRIN1 | |
| SCHEMBL4720752 | 0.88 | LGALS3 (0.34) | KCNK3GRIN2BP2RX7CNR2 | |
| SCHEMBL14102047 | 0.82 | AR (0.34) | TRPM2AR | |
| SCHEMBL4718895 | 0.76 | CYP3A4 (0.32) | C5AR1 | |
| SCHEMBL4722852 | 0.75 | GRIN1 (0.34) | KCNK3GRIN2BGRIN1 | |
| SCHEMBL4718914 | 0.75 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL4718912 | 0.75 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL4724182 | 0.75 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL4719091 | 0.74 | F10 (0.36) | P2RX7 | |
| SCHEMBL4719085 | 0.74 | F10 (0.36) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953147-A1 | HETEROCYCLIC COMPOUND AND MEDICINAL APPLICATION THEREOF | Japan Tobacco, Inc. (JP) | 2008-08-06 | — | — | EP | disclosed |