Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410989 | 0.92 | BRD4 (0.31) | — | |
| SCHEMBL14105640 | 0.90 | CYP19A1 (0.33) | — | |
| SCHEMBL7547192 | 0.89 | BACE1 (0.30) | — | |
| SCHEMBL7562801 | 0.84 | PGR (0.32) | — | |
| SCHEMBL7554270 | 0.83 | — | — | |
| SCHEMBL7550473 | 0.83 | — | — | |
| SCHEMBL13081303 | 0.82 | GABRA1 (0.30) | — | |
| SCHEMBL14105457 | 0.82 | XDH (0.33) | — | |
| SCHEMBL7561438 | 0.82 | BACE1 (0.31) | — | |
| SCHEMBL14105728 | 0.81 | TDP2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008103351-A2 | HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS | SCHERING CORPORATION (US) | 2008-08-28 | — | — | WO | disclosed |