SCHEMBL14112993

SCHEMBL14112993

Cc1cccc(-n2c(S)nc3ccccc32)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.50
HTT P42858 1/20 0.50
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
KDM4E B2RXH2 2/20 0.49
ADORA3 P0DMS8 1/20 0.45
ADORA2A P29274 1/20 0.45
ADORA1 P30542 1/20 0.45
HPGD P15428 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
ALDH1A1 P00352 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
LMNA P02545 2/20 0.43
PLA2G1B P04054 1/20 0.43
ATG4B Q9Y4P1 1/20 0.43
TP53 P04637 5/20 0.43
USP2 O75604 1/20 0.43
POLB P06746 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19275967 0.84 MAPK1 (0.72) MAPK1HTTMEN1KMT2AKDM4E
SCHEMBL1104437 0.82 L3MBTL1 (0.56) MAPK1HTTMEN1KMT2AADORA3
SCHEMBL14112991 0.82 RPS6KB1 (0.56) MAPK1HTTADORA2AADORA1SMN1; SMN2
SCHEMBL889831 0.81 MAPK1 (0.61) MAPK1HTTMEN1KMT2AKDM4E
SCHEMBL23652406 0.81 KDM4E (0.55) MAPK1HTTMEN1KMT2AKDM4E
SCHEMBL22926671 0.80 ESR1 (0.60) MAPK1HTTMEN1KMT2AKDM4E
SCHEMBL27949768 0.80 MAPK1 (0.59) MAPK1HTTMEN1KMT2AKDM4E
SCHEMBL5026794 0.80 LMNA (0.64) MEN1KMT2AHPGDSMN1; SMN2ALDH1A1
SCHEMBL14557061 0.79 MAPK1 (0.53) MAPK1HTTMEN1KMT2AHPGD
SCHEMBL13863180 0.79 ALDH1A1 (0.51) MAPK1HTTKDM4ESMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080160452-A1 Developer for light sensitive planographic printing plate material and manufacturing process of planographic printing plate employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-03 US disclosed
US-20080160452-A1 Developer for light sensitive planographic printing plate material and manufacturing process of planographic printing plate employing the same KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2008-07-03 US disclosed