Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 7/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2452663 | 0.85 | ALOX15 (0.58) | HRH4MAPTALDH1A1ALOX15GLA | |
| SCHEMBL16235908 | 0.83 | HRH4 (0.56) | XDHHRH4CYP1A2MAPT | |
| SCHEMBL22396281 | 0.82 | HRH4 (0.59) | HRH4USP2ALDH1A1KDM4E | |
| SCHEMBL14115024 | 0.81 | XDH (0.56) | XDHSYKCYP1A2MAPTALDH1A1 | |
| SCHEMBL14127307 | 0.81 | CNR2 (0.46) | HRH4ABL1MAPTUSP2ALDH1A1 | |
| SCHEMBL1277485 | 0.79 | XDH (0.63) | XDHHRH4MAPT | |
| SCHEMBL3258615 | 0.76 | XDH (0.45) | XDHHRH4SYKCYP1A2ABL1 | |
| SCHEMBL3283667 | 0.76 | NSD2 (0.61) | XDHHRH4ABL1SRCALDH1A1 | |
| SCHEMBL20605176 | 0.75 | XDH (0.68) | XDHHRH4SYKCYP1A2MAPT | |
| SCHEMBL3963537 | 0.73 | F7 (0.66) | XDHHRH4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080167476-A1 | Process for the preparation of 2-substituted-7-Boryl indoles and compounds | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2008-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167476-A1 | Process for the preparation of 2-substituted-7-Boryl indoles and compounds | INMT, IDO2, IDO1 | XDH 1998/4885HRH4 3805/4885SYK 2318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.