Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.47 |
| ▸ | ADH5 | P11766 | 2/20 | 0.47 |
| ▸ | RAF1 | P04049 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17678908 | 0.83 | PTK2 (0.46) | PTK2HPGDSSLC22A12ADH5RAF1 | |
| SCHEMBL18470671 | 0.77 | XDH (0.50) | PTK2HPGDSSLC22A12ADH5 | |
| SCHEMBL21941742 | 0.74 | ADH5 (0.61) | SLC22A12ADH5ALDH1A1GAATP53 | |
| SCHEMBL3584374 | 0.73 | ADH5 (0.59) | HPGDSADH5ALDH1A1TP53 | |
| SCHEMBL12457517 | 0.73 | PTK2 (0.64) | PTK2ADH5RAF1ALDH1A1HCAR2 | |
| SCHEMBL1458943 | 0.70 | ATM (0.58) | PTK2ADH5ALDH1A1TP53 | |
| SCHEMBL21941743 | 0.70 | NOTUM (0.60) | ADH5ALDH1A1TP53 | |
| SCHEMBL14092293 | 0.70 | TP53 (0.49) | PTK2HPGDSADH5ALDH1A1HCAR2 | |
| SCHEMBL17670047 | 0.69 | MAP4K4 (0.51) | PTK2HPGDSADH5ALDH1A1 | |
| SCHEMBL21941741 | 0.68 | ALDH1A1 (0.79) | SLC22A12ADH5ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414055-B2 | Inhibitors of Akt activity | MERCK & CO., INC. (US) | 2008-08-19 | — | — | US | disclosed |