Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | AKR1B10 | O60218 | 4/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MET | P08581 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14123763 | 0.92 | THRB (0.44) | THRBHCAR2AKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL14123736 | 0.87 | CA12 (0.40) | THRBHCAR2AKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL14123773 | 0.82 | THRB (0.37) | THRBALDH1A1TP53TSHRHIF1A | |
| SCHEMBL14123747 | 0.81 | THRB (0.44) | THRBHCAR2AKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL16518669 | 0.80 | HCAR2 (0.40) | THRBHCAR2AKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL14123766 | 0.79 | HCAR2 (0.41) | THRBHCAR2ALDH1A1KDM4ELMNA | |
| SCHEMBL22349210 | 0.79 | ALOX5 (0.42) | THRBHCAR2AKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL20733442 | 0.79 | THRB (0.55) | THRBHCAR2AKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL9915737 | 0.79 | THRB (0.55) | THRBHCAR2AKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL11987130 | 0.78 | THRB (0.49) | THRBHCAR2AKR1B10AKR1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8962227-B2 | Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, method of producing electrophotographic photosensitive member, and urea compound | CANON KABUSHIKI KAISHA (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20120301177-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND UREA COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2012-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120301177-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, ELECTROPHOTOGRAPHIC APPARATUS, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND UREA COMPOUND | SLC14A1, ITCH, UROD | THRB 4300/4885HCAR2 3166/4885AKR1B10 1072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.