Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 2/20 | 0.44 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL819498 | 0.91 | TP53 (0.70) | TP53MDM2LMNAPOLBHTT | |
| SCHEMBL15461422 | 0.89 | PRCP (0.50) | TP53MDM2LMNAPOLBHTT | |
| SCHEMBL2936024 | 0.84 | TP53 (0.61) | TP53MDM2SIGMAR1 | |
| SCHEMBL7107798 | 0.81 | TP53 (0.58) | TP53MDM2LMNAPOLBHTT | |
| Bromide SCHEMBL11782713 | 0.81 | TP53 (0.51) | TP53MDM2LMNAPOLBHTT | |
| SCHEMBL7150920 | 0.79 | TP53 (0.56) | TP53MDM2LMNAPOLBHTT | |
| SCHEMBL14373042 | 0.79 | TP53 (0.52) | TP53MDM2LMNAPOLBHTT | |
| SCHEMBL14373274 | 0.79 | RORC (0.58) | TP53MDM2LMNAPOLBHTT | |
| SCHEMBL18719826 | 0.79 | SIGMAR1 (0.59) | TP53MDM2LMNAPOLBHTT | |
| SCHEMBL14373087 | 0.76 | TP53 (1.00) | TP53MDM2POLBHTTRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093272-A2 | CONTROLLED RELEASE OF ACTIVE ALDEHYDES AND KETONES FROM EQUILIBRATED DYNAMIC MIXTURES | FIRMENICH SA (CH) | 2008-08-07 | — | — | WO | disclosed |