SCHEMBL819498

SCHEMBL819498

c1ccc(CN2CCN(Cc3ccccc3)C2c2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.70
MDM2 Q00987 1/20 0.70
SIGMAR1 Q99720 1/20 0.50
RORC P51449 1/20 0.50
POLB P06746 1/20 0.49
LMNA P02545 1/20 0.49
HTT P42858 1/20 0.49
RECQL P46063 1/20 0.47
ACHE P22303 1/20 0.44
CYP2C19 P33261 1/20 0.44
GBA1 P04062 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2936024 0.92 TP53 (0.61) TP53MDM2SIGMAR1RECQL
SCHEMBL14124508 0.91 TP53 (0.60) TP53MDM2SIGMAR1RORCPOLB
SCHEMBL7107798 0.89 TP53 (0.58) TP53MDM2SIGMAR1RORCPOLB
SCHEMBL14373087 0.83 TP53 (1.00) TP53MDM2RORCPOLBHTT
SCHEMBL7150920 0.83 TP53 (0.56) TP53MDM2SIGMAR1RORCPOLB
SCHEMBL14373274 0.83 RORC (0.58) TP53MDM2SIGMAR1RORCPOLB
SCHEMBL14373042 0.83 TP53 (0.52) TP53MDM2POLBLMNAHTT
SCHEMBL18719826 0.83 SIGMAR1 (0.59) TP53MDM2SIGMAR1RORCPOLB
Bromide SCHEMBL11782713 0.82 TP53 (0.51) TP53MDM2SIGMAR1POLBLMNA
SCHEMBL14373050 0.81 TP53 (0.61) TP53MDM2POLBCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263631-A1 PRO-PERFUME COMPOSITIONS FIRMENICH SA (CH) 2025-08-21 US claimed
US-20230024269-A1 Pro-Perfume Compositions FIRMENICH SA (CH) 2023-01-26 US claimed
EP-4034073-A1 PRO-PERFUME COMPOSITIONS Firmenich SA (CH) 2022-08-03 EP claimed
CN-114727924-A Pro-fragrance compositions 弗门尼舍有限公司 2022-07-08 CN claimed
WO-2021123144-A1 PRO-PERFUME COMPOSITIONS FIRMENICH SA (CH) 2021-06-24 WO claimed
EP-4711010-A2 PRO-PERFUME COMPOSITIONS Firmenich SA (CH) 2026-03-18 EP disclosed
US-20250263631-A1 PRO-PERFUME COMPOSITIONS FIRMENICH SA (CH) 2025-08-21 US disclosed
US-12325839-B2 Pro-perfume compositions FIRMENICH SA (CH) 2025-06-10 US disclosed
US-20230024269-A1 Pro-Perfume Compositions FIRMENICH SA (CH) 2023-01-26 US disclosed
EP-4034073-A1 PRO-PERFUME COMPOSITIONS Firmenich SA (CH) 2022-08-03 EP disclosed
CN-114727924-A Pro-fragrance compositions 弗门尼舍有限公司 2022-07-08 CN disclosed
WO-2021123144-A1 PRO-PERFUME COMPOSITIONS FIRMENICH SA (CH) 2021-06-24 WO disclosed
EP-0587901-A1 DEVELOPING AGENT FOR HEAT FIXING TYPE ELECTROPHOTOGRAPHY MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-03-23 EP disclosed
EP-0585869-A1 Solid titanium catalyst component for olefin polymerization, process for preparing the same, catalyst for olefin polymerization and process for olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-03-09 EP disclosed
EP-0536503-A2 Olefin polymer composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-04-14 EP disclosed
CN-1070651-A Catalyst for olefin polymerization and olefin polymer MITSUI PETROCHEMICAL IND (JP) 1993-04-07 CN disclosed
EP-0534119-A2 Prepolymerized olefin polymerization catalyst and olefin polymerization process MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-03-31 EP disclosed
CN-1057656-A Solid titanium catalyst component for olefin polymerization, olefin polymerization catalyst, prepolymerized polyolefin-containing catalyst, and process for olefin polymerization MITSUI PETROCHEMICAL IND (JP) 1992-01-08 CN disclosed
EP-0452156-A2 Solid titanium catalyst component for olefin polymerization, olefin polymerization catalyst, prepolymerized polyolefin-containing catalyst and method of olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-10-16 EP disclosed
EP-0086645-B1 CATALYST COMPOSITION AND PROCESS FOR POLYMERIZING OLEFINS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1986-09-24 EP disclosed