SCHEMBL1412653

SCHEMBL1412653

C=C(C)C(=S)OOCC(C)(C)COC(=O)CCCCC(=O)OCC(C)(C)COOC(=S)C(=C)C

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
P2RY10 O00398 1/20 0.31
GPR34 Q9UPC5 1/20 0.31
DGKA P23743 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1412680 0.85 TSHR (0.33) P2RY10GPR34DGKATSHR
SCHEMBL1412663 0.79 TSHR (0.36) P2RY10GPR34DGKATSHR
SCHEMBL259235 0.76 TSHR (0.38) P2RY10GPR34DGKATSHR
SCHEMBL1172670 0.73 TSHR (0.38) P2RY10GPR34DGKATSHR
SCHEMBL2910105 0.73 TSHR (0.37) P2RY10GPR34DGKATSHR
SCHEMBL13343446 0.70 DGKA (0.41) P2RY10GPR34DGKATSHR
SCHEMBL855142 0.70 DGKA (0.61) P2RY10GPR34DGKATSHR
SCHEMBL4211949 0.70 TSHR (0.48) TSHR
SCHEMBL28087702 0.69 TSHR (0.41) TSHR
SCHEMBL1881320 0.69 DGKA (0.64) P2RY10GPR34DGKATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9159356-B2 Non-resonant two-photon absorption recording material, non-resonant polymer two-photon absorption optical information recording medium, and recording/reproducing method FUJIFILM CORPORATION (JP) 2015-10-13 US disclosed
US-20140078878-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL, NON-RESONANT POLYMER TWO-PHOTON ABSORPTION OPTICAL INFORMATION RECORDING MEDIUM, AND RECORDING/REPRODUCING METHOD FUJIFILM CORPORATION (JP) 2014-03-20 US disclosed
EP-2043096-B1 Two-photon absorption recording material containing dye having polymerizable group FUJIFILM CORP (JP) 2011-03-16 EP disclosed
US-20090088490-A1 TWO-PHOTON ABSORPTION RECORDING MATERIAL CONTAINING DYE HAVING POLYMERIZABLE GROUP FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
EP-2043096-A1 Two-photon absorption recording material containing dye having polymerizable group FUJIFILM Corporation (JP) 2009-04-01 EP disclosed
US-7112616-B2 Two-photon absorbing polymerizable composition and polymerization process thereof FUJI PHOTO FILM CO., LTD. (JP) 2006-09-26 US disclosed
US-20040204513-A1 Two-photon absorbing polymerizable composition and polymerization process thereof FUJI PHOTO FILM CO., LTD. 2004-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090088490-A1 TWO-PHOTON ABSORPTION RECORDING MATERIAL CONTAINING DYE HAVING POLYMERIZABLE GROUP DCX, SLC18A2, KCNN2 P2RY10 237/4885GPR34 1985/4885DGKA 3130/4885
US-20140078878-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL, NON-RESONANT POLYMER TWO-PHOTON ABSORPTION OPTICAL INFORMATION RECORDING MEDIUM, AND RECORDING/REPRODUCING METHOD PUF60, PARG, FHIT P2RY10 13/4885GPR34 576/4885DGKA 3340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.