Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 12/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.42 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12748512 | 0.85 | ALDH1A1 (0.52) | CHRM2CHRM1CHRM3TDP1 | |
| Hydrochloric Acid SCHEMBL1474973 | 0.84 | ALDH1A1 (0.51) | CHRM2CHRM1CHRM3TDP1KDM1A | |
| Hydrochloric Acid SCHEMBL2779123 | 0.80 | BCL9 (0.43) | — | |
| SCHEMBL14127692 | 0.78 | RBP4 (0.53) | RBP4 | |
| SCHEMBL16770667 | 0.78 | SCN9A (0.58) | — | |
| SCHEMBL7649618 | 0.78 | ALDH1A1 (0.51) | RBP4SCN8ASCN10A | |
| SCHEMBL27599474 | 0.78 | ALDH1A1 (0.50) | CHRM3IRAK4 | |
| SCHEMBL1475689 | 0.77 | SLC6A4 (0.49) | CHRM2CHRM1CHRM3TDP1KDM1A | |
| SCHEMBL18682185 | 0.77 | SCN9A (0.42) | IRAK4 | |
| Hydrochloric Acid SCHEMBL16759499 | 0.77 | SCN9A (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140088124-A1 | IMIDAZOLE DERIVATIVES | INTERVET INC. | 2014-03-27 | — | — | US | disclosed |
| US-20140088124-A1 | IMIDAZOLE DERIVATIVES | INTERVET INC. | 2014-03-27 | — | — | US | disclosed |
| US-20140088124-A1 | IMIDAZOLE DERIVATIVES | INTERVET INC. | 2014-03-27 | — | — | US | disclosed |
| WO-2012162794-A1 | CONJUGATED COPOLYMERS USEFUL IN ELECTRONICS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2012-12-06 | — | — | WO | disclosed |
| WO-2012164071-A1 | IMIDAZOLE DERIVATIVES | INTERVET INTERNATIONAL B.V. (NL) | 2012-12-06 | — | — | WO | disclosed |
| WO-2012164071-A1 | IMIDAZOLE DERIVATIVES | INTERVET INTERNATIONAL B.V. (NL) | 2012-12-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140088124-A1 | IMIDAZOLE DERIVATIVES | DGAT1, DGAT2, SOAT1 | CHRM2 4064/4885CHRM1 3934/4885CHRM3 4355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.