Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20304443 | 0.84 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL29780578 | 0.84 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL6125251 | 0.82 | LMNA (0.53) | RAB9ANPC1SMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL14136369 | 0.81 | ALDH1A1 (0.45) | RAB9ANPC1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL10267105 | 0.81 | USP30 (0.47) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL2708939 | 0.81 | MPO (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL29892036 | 0.81 | MPO (0.59) | RAB9ANPC1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL26226192 | 0.81 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL13810503 | 0.81 | LMNA (0.61) | ALDH1A1NPSR1TP53THRBMAPT | |
| SCHEMBL6125245 | 0.80 | LMNA (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023184327-A1 | KINASE INHIBITORS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2023-10-05 | — | — | WO | disclosed |
| WO-2021030620-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2021-02-18 | — | — | WO | disclosed |
| EP-1950199-A1 | Proline derivatives and use thereof as drugs | Mitsubishi Tanabe Pharma Corporation (JP) | 2008-07-30 | — | — | EP | disclosed |