Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.51 |
| ▸ | ITGAV | P06756 | 4/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.51 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.51 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.47 |
| ▸ | MC4R | P32245 | 7/20 | 0.47 |
| ▸ | MC5R | P33032 | 7/20 | 0.47 |
| ▸ | MC3R | P41968 | 7/20 | 0.47 |
| ▸ | MC1R | Q01726 | 7/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | FURIN | P09958 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14096840 | 0.93 | MC4R (0.51) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL12837665 | 0.90 | CTSG (0.51) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL13656565 | 0.90 | CTSG (0.51) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL11926071 | 0.84 | CTSG (0.55) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL14885782 | 0.84 | ITGB3 (0.61) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL16177741 | 0.84 | ITGB3 (0.61) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL13659869 | 0.84 | CTSG (0.54) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL12647201 | 0.83 | MC4R (0.49) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL7744481 | 0.82 | ITGB3 (0.64) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL279121 | 0.82 | ITGB3 (0.64) | ITGB3ITGAVITGB1ITGA5ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080187493-A1 | a targeting vector which binds to receptors associated with integrin receptors, angiogenesis; contrast agents; diagnosis of malignant diseases, heart diseases, inflammation-related diseases, rheumatoid arthritis and Kaposi's sarcoma | GE HEALTHCARE AS (NO) | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080187493-A1 | a targeting vector which binds to receptors associated with integrin receptors, angiogenesis; contrast agents; diagnosis of malignant diseases, heart diseases, inflammation-related diseases, rheumatoid arthritis and Kaposi's sarcoma | KDR, VCAM1, FLT1 | ITGB3 16/4885ITGAV 6/4885ITGB1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.