Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12310509 | 0.88 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL15314942 | 0.84 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL8381526 | 0.84 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL17931005 | 0.81 | AKR1C3 (0.51) | ALDH1A1TDP1CYP3A4MAPK1AKR1C3 | |
| SCHEMBL28503829 | 0.81 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1TSHRTDP1CYP3A4 | |
| SCHEMBL20897393 | 0.81 | CTSV (0.52) | L3MBTL1ALDH1A1TDP1MAPTKMT2A | |
| SCHEMBL29172544 | 0.79 | MEN1 (0.48) | L3MBTL1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL10102460 | 0.78 | ALDH1A1 (0.46) | L3MBTL1ALDH1A1TDP1MAPTKMT2A | |
| SCHEMBL2089147 | 0.78 | MEN1 (0.54) | L3MBTL1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL874114 | 0.78 | MEN1 (0.54) | L3MBTL1ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315715-B1 | QUINAZOLINE DERIVATIVES AS KINASE INHIBITORS | MILLENNIUM PHARM INC (US) | 2008-07-23 | — | — | EP | disclosed |