Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 4/20 | 0.63 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29097098 | 0.88 | DRD1 (0.59) | DRD1ALDH1A3ALDH1A1CYP2A6STS | |
| SCHEMBL607344 | 0.83 | DRD1 (0.88) | DRD1ALDH1A3ALDH1A1CYP2A6STS | |
| SCHEMBL6466375 | 0.82 | DRD1 (0.37) | DRD1ALDH1A3ALDH1A1LMNAKMT2A | |
| SCHEMBL6279527 | 0.80 | DRD1 (0.59) | DRD1ALDH1A3ALDH1A1CYP2A6STS | |
| SCHEMBL4412891 | 0.78 | DRD1 (1.00) | DRD1ALDH1A3ALDH1A1CYP2A6STS | |
| SCHEMBL2536930 | 0.77 | DRD1 (0.51) | DRD1ALDH1A1LMNASMN1; SMN2KMT2A | |
| Benzaldehyde SCHEMBL28192272 | 0.76 | DRD1 (0.76) | DRD1ALDH1A3ALDH1A1CYP2A6KDM4E | |
| SCHEMBL4928878 | 0.76 | DRD1 (0.59) | DRD1ALDH1A3ALDH1A1CYP2A6STS | |
| SCHEMBL384361 | 0.74 | ALDH1A3 (1.00) | DRD1ALDH1A3ALDH1A1CYP2A6STS | |
| SCHEMBL14016002 | 0.74 | ALDH1A3 (0.76) | DRD1ALDH1A3ALDH1A1CYP2A6STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981658-A | Novel contrast agents for magnetic resonance imaging | 拜耳股份有限公司 | 2023-10-31 | — | — | CN | disclosed |
| EP-2025661-B1 | FLUOROALKYLOXY-CONTAINING COMBRETASTATIN DERIVATIVES, PREPARATION AND USE THEREOF | ZHEJIANG DADE PHARMACEUTICAL GROUP CO LTD (CN) | 2011-03-16 | — | — | EP | disclosed |
| US-7786098-B2 | Fluoroalkoxycombretastatin derivatives, method for producing the same and use thereof | ZHEJIANG DADE PHARMACEUTICAL GROUP CO. LTD. (CN) | 2010-08-31 | — | — | US | disclosed |
| EP-2025661-A1 | FLUOROALKYLOXY-CONTAINING COMBRETASTATIN DERIVATIVES, PREPARATION AND USE THEREOF | Zhejiang Dade Pharmaceutical Group Co., Ltd. (CN) | 2009-02-18 | — | — | EP | disclosed |
| US-20080306027-A1 | Fluoroalkoxycombretastatin Derivatives, Method For Producing the Same and Use Thereof | ZHEJIANG DADE PHARMACEUTICAL GROUP CO., LTD. (CN) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306027-A1 | Fluoroalkoxycombretastatin Derivatives, Method For Producing the Same and Use Thereof | TUBB, TUBB1, TUBB3 | DRD1 4730/4885ALDH1A3 4277/4885ALDH1A1 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.