SCHEMBL141490

SCHEMBL141490

CC1=Cc2c(-c3cc(Cl)cc(Cl)c3)cccc2C1[Zr](Cl)(Cl)(C1C(C)=Cc2c(-c3cc(Cl)cc(Cl)c3)cccc21)[SiH](C)C

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.31
HTR7 P34969 1/20 0.31
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL139278 0.91 ESR2 (0.35) HTR1AHTR7
SCHEMBL5952632 0.88
SCHEMBL273297 0.88
SCHEMBL139507 0.88 PTGS2 (0.31)
SCHEMBL5951483 0.86 DRD2 (0.31) HTR1AHTR7
SCHEMBL5843091 0.86
SCHEMBL136348 0.85 PDCD1 (0.30)
SCHEMBL1583086 0.85 HTR1A (0.30) HTR1AHTR7
SCHEMBL5951381 0.85 BRD4 (0.32) HTR7
SCHEMBL139769 0.85 ENPP3 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2415792-B1 COPOLYMER OF OLEFIN AND CONJUGATED DIENE, AND PROCESS FOR PRODUCING SAME MITSUI CHEMICALS INC (JP) 2014-11-12 EP disclosed
CN-102356100-B Copolymer of olefin and conjugated diene and preparation method thereof MITSU CHEMICALS INC 2014-01-08 CN disclosed
US-8513368-B2 Copolymer of olefin and conjugated diene, and process for producing the same MITSUI CHEMICALS, INC. (JP) 2013-08-20 US disclosed
US-20120059135-A1 COPOLYMER OF OLEFIN AND CONJUGATED DIENE, AND PROCESS FOR PRODUCING THE SAME MITSUI CHEMICALS, INC. (JP) 2012-03-08 US disclosed