Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL5956145 | 0.87 | ALDH1A1 (0.40) | TSHRHSD17B10POLBLMNASMN1; SMN2 | |
| SCHEMBL20649 | 0.84 | ALDH1A1 (0.35) | TSHRHSD17B10LMNAALDH1A1 | |
| SCHEMBL7694424 | 0.81 | — | — | |
| Ammonia Solution, Strong SCHEMBL5487461 | 0.81 | ALDH1A1 (0.33) | TSHRHSD17B10LMNAALDH1A1 | |
| Water SCHEMBL2471732 | 0.81 | ALDH1A1 (0.33) | TSHRHSD17B10LMNAALDH1A1 | |
| Bicarbonate SCHEMBL177964 | 0.81 | CA1 (0.39) | TSHRHSD17B10LMNAALDH1A1 | |
| Tetrahydrofuran SCHEMBL8679878 | 0.79 | POLB (0.39) | TSHRPOLBLMNASMN1; SMN2MEN1 | |
| Hydrazine SCHEMBL10344909 | 0.78 | TSHR (0.33) | TSHRHSD17B10LMNAALDH1A1 | |
| Ethylene SCHEMBL8927826 | 0.78 | TSHR (0.38) | TSHRHSD17B10ALDH1A1 | |
| Benzene SCHEMBL11037140 | 0.78 | TDP1 (0.42) | TSHRHSD17B10LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2294042-B1 | PROCESS FOR THE PREPARATION OF ALKYLENE GLYCOL | SHELL INT RESEARCH (NL) | 2018-08-08 | — | — | EP | disclosed |
| EP-2294042-A1 | PROCESS FOR THE PREPARATION OF ALKYLENE GLYCOL | Shell Internationale Research Maatschappij B.V. (NL) | 2011-03-16 | — | — | EP | disclosed |
| WO-2009124988-A1 | PROCESS FOR THE PREPARATION OF ALKYLENE GLYCOL | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2009-10-15 | — | — | WO | disclosed |