SCHEMBL14152253

SCHEMBL14152253

CCO[Si](CCCCCNC)(OCC)OCC

nearest known ligand 0.46

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.46
SIGMAR1 Q99720 2/20 0.31
KDM4A O75164 1/20 0.30
KDM4C Q9H3R0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14151723 1.00 EPHX1 (0.46) EPHX1SIGMAR1KDM4AKDM4C
SCHEMBL200380 0.98 EPHX1 (0.42) EPHX1
SCHEMBL111512 0.91 EPHX1 (0.39) EPHX1
SCHEMBL28540736 0.85 EPHX1 (0.39) EPHX1
SCHEMBL28001384 0.84 EPHX1 (0.50) EPHX1
SCHEMBL1109619 0.83 LMNA (0.32)
SCHEMBL2580826 0.83 LMNA (0.32)
SCHEMBL20478202 0.83 LMNA (0.32)
SCHEMBL20478199 0.83 LMNA (0.32)
SCHEMBL477797 0.83 LMNA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9028603-B2 Anti-fouling coating compositions and methods for preventing the fouling of surfaces THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2015-05-12 US claimed
US-20120312192-A1 Anti-Fouling Coating Compositions and Methods For Preventing the Fouling of Surfaces NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2012-12-13 US claimed
US-12624168-B2 Methods for making polyfunctional organosiloxanes and compositions containing same DOW SILICONES CORPORATION (US) 2026-05-12 US disclosed
US-12534650-B2 Composition for preparing a release coating and method of preparing coated substrate DOW SILICONES CORPORATION (US) 2026-01-27 US disclosed
EP-4519346-B1 SILICONE-POLYETHER COPOLYMER, SEALANTS COMPRISING SAME, AND RELATED METHODS DOW SILICONES CORP (US) 2026-01-14 EP disclosed
US-20250354030-A1 CURABLE SILICONE-BASED GEL COMPOSITION, CURED GEL THEREOF, ENCAPSULANT AGENT, ELECTRONIC ARTICLE AND PROTECTION METHOD FOR SEMICONDUCTOR CHIP DOW SILICONES CORP (US) 2025-11-20 US disclosed
EP-3645607-B1 METHOD FOR HYDROSILYLATION OF ALIPHATICALLY UNSATURATED ALKOXYSILANES AND HYDROGEN TERMINATED ORGANOSILOXANE OLIGOMERS TO PREPARE ALKOXYSILYL TERMINATED POLYMERS USEFUL FOR FUNCTIONALIZING POLYORGANOSILOXANES USING AN IRIDIUM CATALYST DOW SILICONES CORP (US) 2025-11-05 EP disclosed
US-12441844-B2 Methods for making polyfunctional organosiloxanes and compositions containing same DOW GLOBAL TECHNOLOGIES LLC (US) 2025-10-14 US disclosed
US-12428561-B2 Silicone-polyether copolymer, sealants comprising same, and related methods DOW SILICONES CORPORATION (US) 2025-09-30 US disclosed
EP-4612237-A1 THERMALLY-CONDUCTIVE SILICONE COMPOSITION, THERMALLY-CONDUCTIVE MEMBER, AND HEAT DISSIPATION STRUCTURE Dow Silicones Corporation (US) 2025-09-10 EP disclosed
US-20250257169-A1 COMPOSITION, URETHANE PREPOLYMER, AND RELATED METHODS AND USES DOW SILICONES CORP (US) 2025-08-14 US disclosed
US-20190233674-A1 Hydrophobic Xerogel Film and Method of Use Thereof For Reducing Condensation MIRAPAKON INC (CA) 2019-08-01 US disclosed
EP-3510118-A1 HYDROPHOBIC XEROGEL FILM AND METHOD OF USE THEREOF FOR REDUCING CONDENSATION Mirapakon Inc. (CA) 2019-07-17 EP disclosed
EP-3455506-A1 HYDROPHOBIC XEROGEL FILM AND METHOD OF USE THEREOF FOR REDUCING DRAG Mirapakon Inc. (CA) 2019-03-20 EP disclosed
US-20180362778-A1 MIXED TRANSITION METAL OXIDES SILICA XEROGELS AS ANTIFOULING/FOULING RELEASE SURFACES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2018-12-20 US disclosed
WO-2018045467-A1 HYDROPHOBIC XEROGEL FILM AND METHOD OF USE THEREOF FOR REDUCING CONDENSATION MIRAPAKON INC. (CA) 2018-03-15 WO disclosed
WO-2017193220-A1 HYDROPHOBIC XEROGEL FILM AND METHOD OF USE THEREOF FOR REDUCING DRAG MIRAPAKON INC. (CA) 2017-11-16 WO disclosed
WO-2017100629-A1 MIXED TRANSITION METAL OXIDES SILICA XEROGELS AS ANTIFOULING/FOULING RELEASE SURFACES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2017-06-15 WO disclosed
US-9028603-B2 Anti-fouling coating compositions and methods for preventing the fouling of surfaces THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2015-05-12 US disclosed
US-20120312192-A1 Anti-Fouling Coating Compositions and Methods For Preventing the Fouling of Surfaces NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2012-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534650-B2 Composition for preparing a release coating and method of preparing coated substrate COL2A1, MSR1, COL1A1 EPHX1 3044/4885SIGMAR1 5/4885KDM4A 1596/4885
US-12624168-B2 Methods for making polyfunctional organosiloxanes and compositions containing same HAO2, H1-2, HRH2 EPHX1 1171/4885SIGMAR1 302/4885KDM4A 476/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.