Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 16/20 | 0.50 |
| ▸ | CHRM1 known ✓ | P11229 | 9/20 | 0.50 |
| ▸ | CHRM3 known ✓ | P20309 | 12/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 12/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.36 |
| ▸ | PRKCG | P05129 | 2/20 | 0.36 |
| ▸ | PRKCB | P05771 | 2/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.36 |
| ▸ | PRKCH | P24723 | 2/20 | 0.36 |
| ▸ | PRKCI | P41743 | 2/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20162231 | 0.97 | CHRM2 (0.52) | CHRM2CHRM5CHRM1TSHRMAPK1 | |
| Iodide SCHEMBL11797425 | 0.94 | CHRM2 (0.54) | CHRM2CHRM5CHRM1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL194196 | 0.87 | CHRM2 (0.45) | CHRM2CHRM5CHRM1TSHRMAPK1 | |
| SCHEMBL19164287 | 0.86 | CHRM2 (0.48) | CHRM2CHRM5CHRM1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL10903569 | 0.85 | PRKD3 (0.46) | CHRM2CHRM5CHRM1TSHRMAPK1 | |
| SCHEMBL587971 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL28138219 | 0.83 | CHRM2 (0.42) | CHRM2CHRM5CHRM1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL7942359 | 0.83 | PRKD3 (0.45) | CHRM2CHRM5CHRM1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL286149 | 0.82 | CHRM2 (0.67) | CHRM2CHRM5CHRM1TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL10723477 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118475659-A | Resin particle dispersion for inkjet printing | 爱克发有限公司 | 2024-08-09 | — | — | CN | disclosed |
| US-8217201-B2 | Process for preparing quaternary alkammonium halides | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-07-10 | — | — | US | disclosed |
| EP-2054371-B1 | PROCESS FOR PREPARING QUATERNARY ALKYLAMMONIUM HALIDES | DOW GLOBAL TECHNOLOGIES INC (US) | 2011-03-09 | — | — | EP | disclosed |
| US-20100160684-A1 | PROCESS FOR PREPARING QUATERNARY ALKAMMONIUM HALIDES | DOW GLOBAL TECHNOLOGIES LLC | 2010-06-24 | — | — | US | disclosed |
| EP-0731144-B1 | Azo dyes, their production and use | CLARIANT FINANCE BVI LTD (VG) | 2000-08-23 | — | — | EP | disclosed |
| EP-0731146-B1 | Cationic dyes, their production and use | CLARIANT FINANCE BVI LTD (VG) | 1999-10-27 | — | — | EP | disclosed |
| US-5964899-A | Azo dyes, their production and use | CLARIANT FINANCE (BVI) LIMITED (VG) | 1999-10-12 | — | — | US | disclosed |
| US-5766269-A | Cationic dyes, their production and use | CLARIANT FINANCE (BVI) LIMITED (VG) | 1998-06-16 | — | — | US | disclosed |
| EP-0731146-A2 | Cationic dyes, their production and use | Clariant Finance (BVI) Limited (VG) | 1996-09-11 | — | — | EP | disclosed |
| EP-0731144-A2 | Azo dyes, their production and use | Clariant Finance (BVI) Limited (VG) | 1996-09-11 | — | — | EP | disclosed |