Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 13/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 11/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 10/20 | 0.48 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5108598 | 0.87 | OPRL1 (0.52) | HSD17B10BDKRB2OPRL1OPRK1OPRD1 | |
| SCHEMBL173699 | 0.86 | BDKRB2 (0.59) | HSD17B10BDKRB2OPRL1OPRK1OPRD1 | |
| SCHEMBL11876831 | 0.86 | OPRL1 (0.64) | HSD17B10BDKRB2OPRL1OPRK1OPRD1 | |
| SCHEMBL5556302 | 0.85 | OPRM1 (0.53) | HSD17B10BDKRB2OPRL1OPRK1OPRD1 | |
| SCHEMBL12893390 | 0.84 | BDKRB2 (0.74) | HSD17B10BDKRB2OPRL1OPRK1OPRD1 | |
| SCHEMBL12668350 | 0.84 | OPRK1 (0.52) | HSD17B10BDKRB2OPRL1OPRK1OPRD1 | |
| SCHEMBL5782044 | 0.83 | OPRK1 (0.66) | HSD17B10BDKRB2OPRL1OPRK1OPRD1 | |
| SCHEMBL20187016 | 0.82 | HSD17B10 (0.57) | HSD17B10BDKRB2OPRL1OPRK1OPRD1 | |
| SCHEMBL20187220 | 0.81 | OPRL1 (0.63) | HSD17B10BDKRB2OPRL1OPRK1OPRD1 | |
| SCHEMBL1640719 | 0.81 | OPRM1 (0.57) | BDKRB2OPRL1OPRK1OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2291075-A2 | GASTRIN RELEASING PEPTIDE COMPOUNDS | Bracco Imaging S.p.A (IT) | 2011-03-09 | — | — | EP | disclosed |
| WO-2009143101-A2 | GASTRIN RELEASING PEPTIDE COMPOUNDS | BRACCO IMAGING S.P.A. (IT) | 2009-11-26 | — | — | WO | disclosed |