Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3494478 | 0.88 | MEN1 (0.45) | KDM4EPKMTSHRALOX15MEN1 | |
| SCHEMBL3492019 | 0.81 | WNT3A (0.41) | KDM4EPKMTSHRALOX15ATM | |
| SCHEMBL1003119 | 0.79 | OPRD1 (0.52) | KDM4EPKMGPR119TSHRALOX15 | |
| SCHEMBL30762057 | 0.78 | KDM4E (0.48) | KDM4EPKMGPR119TSHRALOX15 | |
| SCHEMBL3494231 | 0.78 | SYK (0.47) | KDM4EPKMTACR1OPRD1OPRK1 | |
| SCHEMBL20493148 | 0.77 | OPRD1 (0.50) | GPR119TSHRALOX15ATMTACR1 | |
| SCHEMBL1446835 | 0.76 | TACR1 (0.60) | KDM4EPKMGPR119TSHRALOX15 | |
| SCHEMBL2375438 | 0.75 | GPR119 (0.50) | PKMGPR119TSHRALOX15ATM | |
| SCHEMBL8762050 | 0.75 | GPR119 (0.44) | KDM4EPKMGPR119TSHRALOX15 | |
| SCHEMBL8202394 | 0.75 | KDM4E (0.50) | KDM4EPKMGPR119TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075110-A1 | SUBSTITUTED PIPERIDINES CONTAINING A HETEROARYLAMIDE OR HETEROARYLPHENYL MOIETY | ASTEX THERAPEUTICS LIMITED (GB) | 2008-06-26 | — | — | WO | disclosed |