Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003119 | 0.93 | OPRD1 (0.52) | GPR119TSHRALOX15ATMTACR1 | |
| SCHEMBL2375967 | 0.90 | PKM (0.56) | GPR119USP30TSHRALOX15ATM | |
| SCHEMBL16112188 | 0.88 | LMNA (0.55) | — | |
| SCHEMBL2185224 | 0.87 | KDM1A (0.46) | TSHRALOX15ATMTACR1OPRD1 | |
| SCHEMBL22793050 | 0.87 | GPR119 (0.49) | GPR119TSHRALOX15ATMTACR1 | |
| SCHEMBL20510831 | 0.87 | MMP13 (0.43) | TSHRALOX15ATMTACR1OPRD1 | |
| SCHEMBL1003393 | 0.87 | MEN1 (0.51) | OPRD1OPRK1 | |
| SCHEMBL24097945 | 0.86 | ALDH1A1 (0.50) | GPR119PKM | |
| SCHEMBL28818611 | 0.85 | OPRD1 (0.47) | GPR119USP30TSHRALOX15ATM | |
| SCHEMBL28818534 | 0.85 | OPRD1 (0.47) | GPR119USP30TSHRALOX15ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2544684-B1 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-1 (DPP-1) | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-24 | — | — | EP | disclosed |
| EP-2544684-A1 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-1 (DPP-1) | Janssen Pharmaceutica, N.V. (BE) | 2013-01-16 | — | — | EP | disclosed |
| US-20110224209-A1 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-1 (DPP-1) | JANSSEN PHARMACEUTICA N.V. (BE) | 2011-09-15 | — | — | US | disclosed |
| WO-2011112685-A1 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-1 (DPP-1) | JANSSEN PHARMACEUTICA NV (BE) | 2011-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224209-A1 | 4,4-DISUBSTITUTED PIPERIDINE DERIVATIVES USEFUL AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-1 (DPP-1) | DPP4, DPP3, DPP7 | GPR119 38/4885USP30 485/4885TSHR 3327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.