⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL992351 | 0.75 | — | — | |
| SCHEMBL5366280 | 0.70 | — | — | |
| SCHEMBL9876709 | 0.68 | — | — | |
| SCHEMBL8919030 | 0.67 | TSHR (0.31) | — | |
| SCHEMBL29028507 | 0.67 | THRB (0.30) | — | |
| SCHEMBL19445479 | 0.67 | — | — | |
| SCHEMBL769441 | 0.66 | TSHR (0.33) | — | |
| SCHEMBL1976528 | 0.63 | — | — | |
| SCHEMBL3501857 | 0.62 | TSHR (0.30) | — | |
| SCHEMBL18048378 | 0.62 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8323888-B2 | Nanoparticles having oligonucleotides attached thereto and uses therefor | NANOSPHERE, INC. (US) | 2012-12-04 | — | — | US | disclosed |
| EP-1294930-B1 | NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR | NANOSPHERE INC (US) | 2011-03-30 | — | — | EP | disclosed |
| EP-1198591-B1 | NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR | NANOSPHERE INC (US) | 2011-03-16 | — | — | EP | disclosed |
| EP-1301625-B1 | NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR | NANOSPHERE INC (US) | 2010-11-03 | — | — | EP | disclosed |
| WO-2001051665-A9 | NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR | NANOSPHERE INC. (US) | 2010-09-23 | — | — | WO | disclosed |
| US-20090325812-A1 | Nanoparticles having oligonucleotides attached thereto and uses therefor | NANOSPHERE, INC. (US) | 2009-12-31 | — | — | US | disclosed |
| EP-1198591-A4 | NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR | NANOSPHERE INC (US) | 2007-10-24 | — | — | EP | disclosed |
| US-7259252-B2 | Nanoparticles having oligonucleotides attached thereto and uses therefor | NANOSPHERE, INC. (US) | 2007-08-21 | — | — | US | disclosed |
| US-7250499-B2 | Nanoparticles having oligonucleotides attached thereto and uses therefor | NANOSPHERE INC. (US) | 2007-07-31 | — | — | US | disclosed |
| US-7208587-B2 | Nanoparticles having oligonucleotides attached thereto and uses therefor | NANOSPHERE, INC. (US) | 2007-04-24 | — | — | US | disclosed |
| US-6403302-B1 | DOUBLE HELICAL NUCLEIC ACID COMPRISING COMPLEMENTARY STRANDS AND OLIGONUCLEOTIDE BOUND TO TARGET SEQUENCE WITHIN; GENETIC ENGINEERING; DIAGNOSING GENE DISORDERS; ANTIPARALLEL ORIENTATION; NON-DENATURING | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-06-11 | — | — | US | disclosed |
| EP-1198591-A1 | NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR | Mirkin, Chad A. (US) | 2002-04-24 | — | — | EP | disclosed |
| US-6361944-B1 | Nanoparticles having oligonucleotides attached thereto and uses therefor | NANOSPHERE, INC. | 2002-03-26 | — | — | US | disclosed |
| WO-2002018643-A2 | NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR | NANOSPHERE INC. (US) | 2002-03-07 | — | — | WO | disclosed |
| WO-2001073123-A2 | NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR | NANOSPHERE INC. (US) | 2001-10-04 | — | — | WO | disclosed |
| WO-2001000876-A9 | NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR | MIRKIN CHAD A (US) | 2001-07-26 | — | — | WO | disclosed |
| WO-2001051665-A2 | NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR | NANOSPHERE INC. (US) | 2001-07-19 | — | — | WO | disclosed |
| US-6262241-B1 | ANTISENSE COMPOUNDS WHICH CLEAVE PHOSPHORODIESTER BONDS AND IMPROVE PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES OF OLIGONUCLEOTIDES, USEFUL IN DIAGNOSING DISEASES | ISIS PHARMACEUTICALS, INC. | 2001-07-17 | — | — | US | disclosed |
| WO-2001000876-A1 | NANOPARTICLES HAVING OLIGONUCLEOTIDES ATTACHED THERETO AND USES THEREFOR | MIRKIN CHAD A (US) | 2001-01-04 | — | — | WO | disclosed |
| EP-0320103-A2 | Compounds for DNA deletion and oligomers used therefor as well as a method for use thereof | AJINOMOTO CO., INC. (JP) | 1989-06-14 | — | — | EP | disclosed |