Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8919030 | 0.79 | TSHR (0.31) | TSHRNLRP3 | |
| SCHEMBL18048378 | 0.69 | TSHR (0.30) | TSHRNLRP3 | |
| SCHEMBL3501857 | 0.69 | TSHR (0.30) | TSHRNLRP3 | |
| SCHEMBL31402658 | 0.69 | TSHR (0.30) | TSHRNLRP3 | |
| SCHEMBL1472140 | 0.67 | — | — | |
| SCHEMBL3565320 | 0.67 | — | — | |
| SCHEMBL1976528 | 0.67 | — | — | |
| SCHEMBL29028507 | 0.67 | THRB (0.30) | — | |
| SCHEMBL19445479 | 0.67 | — | — | |
| SCHEMBL11811303 | 0.67 | TSHR (0.34) | TSHRNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024186176-A1 | METHOD FOR PREPARING MODIFIED NUCLEOSIDES FROM THYMIDINE | 주식회사 압타머사이언스 | 2024-09-12 | — | — | WO | claimed |
| US-20250059227-A1 | ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE OF SAME | RIKEN GENESIS CO., LTD. (JP) | 2025-02-20 | — | — | US | disclosed |
| EP-4458836-A1 | NOVEL ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE OF SAME | Riken Genesis Co., Ltd. (JP) | 2024-11-06 | — | — | EP | disclosed |
| WO-2024186176-A1 | METHOD FOR PREPARING MODIFIED NUCLEOSIDES FROM THYMIDINE | 주식회사 압타머사이언스 | 2024-09-12 | — | — | WO | disclosed |
| US-20230212178-A1 | METHOD OF PRODUCING PHOTOREACTIVE NUCLEOTIDE ANALOG | JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (JP) | 2023-07-06 | — | — | US | disclosed |
| WO-2023127857-A1 | NOVEL ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE OF SAME | 株式会社理研ジェネシス | 2023-07-06 | — | — | WO | disclosed |
| US-20230160849-A1 | Engineered DNA for Molecular Electronics | UNIVERSAL SEQUENCING TECHNOLOGY CORPORATION (US) | 2023-05-25 | — | — | US | disclosed |
| EP-4108670-A1 | BRIDGED NUCLEOSIDE AND NUCLEOTIDE USING SAME | OSAKA UNIVERSITY (JP) | 2022-12-28 | — | — | EP | disclosed |
| US-9221864-B2 | Tricyclic nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2015-12-29 | — | — | US | disclosed |
| US-20150112055-A1 | TRICYCLIC NUCLEIC ACID ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 2015-04-23 | — | — | US | disclosed |
| US-8846637-B2 | Substituted 2′-amino and 2′-thio-bicyclic nucleosides and oligomeric compounds prepared therefrom | ISIS PHARMACEUTICALS, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| US-8796437-B2 | Tetrahydropyran nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2014-08-05 | — | — | US | disclosed |
| US-20130211064-A1 | TETRAHYDROPYRAN NUCLEIC ACID ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 2013-08-15 | — | — | US | disclosed |
| US-8501805-B2 | Substituted alpha-L-bicyclic nucleosides | ISIS PHARMACEUTICALS, INC. (US) | 2013-08-06 | — | — | US | disclosed |
| US-20130131147-A1 | SUBSTITUTED 2'-AMINO AND 2'-THIO-BICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | ISIS PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| US-8440803-B2 | Tetrahydropyran nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2013-05-14 | — | — | US | disclosed |
| US-8278426-B2 | Carbocyclic bicyclic nucleic acid analogs | ISIS PHARMACEUTICALS, INC. (US) | 2012-10-02 | — | — | US | disclosed |
| US-20120071645-A1 | TETRAHYDROPYRAN NUCLEIC ACID ANALOGS | ISIS PHARMACEUTICALS, INC. (US) | 2012-03-22 | — | — | US | disclosed |
| US-20120021515-A1 | OLIGOMERIC COMPOUNDS AND METHODS | ISIS PHARMACEUTICALS, INC. | 2012-01-26 | — | — | US | disclosed |
| US-20110166205-A1 | SUBSTITUTED ALPHA-L-BICYCLIC NUCLEOSIDES | IONIS PHARMACEUTICALS, INC. | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212178-A1 | METHOD OF PRODUCING PHOTOREACTIVE NUCLEOTIDE ANALOG | POLH, POLL, POLM | TSHR 4018/4885NLRP3 3320/4885 |
| US-20130131147-A1 | SUBSTITUTED 2'-AMINO AND 2'-THIO-BICYCLIC NUCLEOSIDES AND OLIGOMERIC COMPOUNDS PREPARED THEREFROM | TYMS, NOP2, TYMP | TSHR 3116/4885NLRP3 2997/4885 |
| US-20120021515-A1 | OLIGOMERIC COMPOUNDS AND METHODS | HNRNPH1, RNASEH1, SNRPE | TSHR 4204/4885NLRP3 2515/4885 |
| US-20250059227-A1 | ARTIFICIAL NUCLEIC ACID, METHOD FOR PRODUCING SAME, AND USE OF SAME | NSUN3, NSUN2, LUC7L2 | TSHR 1945/4885NLRP3 3407/4885 |
| US-20150112055-A1 | TRICYCLIC NUCLEIC ACID ANALOGS | RRM2, RRM1, RNMT | TSHR 2123/4885NLRP3 2626/4885 |
| US-20120071645-A1 | TETRAHYDROPYRAN NUCLEIC ACID ANALOGS | HNRNPM, POLM, RNMT | TSHR 3800/4885NLRP3 3693/4885 |
| US-20110166205-A1 | SUBSTITUTED ALPHA-L-BICYCLIC NUCLEOSIDES | RNMT, HNRNPM, NSUN2 | TSHR 4641/4885NLRP3 4221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.