Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CDA | P32320 | 1/20 | 0.50 |
| ▸ | ATIC | P31939 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25808149 | 0.91 | HPGD (0.46) | HPGDPAX8ATIC | |
| SCHEMBL31685780 | 0.79 | HPGD (0.60) | HPGDPAX8LMNATP53GMNN | |
| SCHEMBL28635586 | 0.78 | HPGD (0.59) | HPGDPAX8LMNATP53GMNN | |
| SCHEMBL14156814 | 0.77 | LMNA (0.48) | LMNATP53SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL22577548 | 0.77 | TYMP (0.66) | ADORA1 | |
| SCHEMBL25808153 | 0.77 | IMPDH2 (0.35) | HPGDPAX8ATICADORA1 | |
| SCHEMBL6746714 | 0.77 | PAX8 (0.58) | HPGDPAX8MAPTLMNATP53 | |
| SCHEMBL22577570 | 0.76 | HPGD (0.34) | HPGDPAX8ADORA1 | |
| SCHEMBL14156805 | 0.75 | LMNA (0.57) | LMNASLC28A1SLC28A2SLC29A1SLC28A3 | |
| Xanthosine SCHEMBL21602879 | 0.75 | HPGD (0.64) | HPGDPAX8MAPTCDAATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7385051-B2 | Fluorescent N2,N3-etheno-purine (2′-deoxy) riboside derivatives and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2008-06-10 | — | — | US | disclosed |
| US-7385051-B2 | Fluorescent N2,N3-etheno-purine (2′-deoxy) riboside derivatives and uses thereof | BAR-LLAN UNIVERSITY (IL) | 2008-06-10 | — | — | US | disclosed |