SCHEMBL1415809

SCHEMBL1415809

O=C(NCCO)OCCOc1cc[c]cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 2/20 0.44
TSHR P16473 1/20 0.44
HRH3 Q9Y5N1 2/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA4 P43681 1/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.40
MAPT P10636 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ACHE P22303 2/20 0.38
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1416262 0.89 SMN1; SMN2 (0.43) RAB9ASMN1; SMN2NPC1TSHRHRH3
SCHEMBL1416277 0.88 SMN1; SMN2 (0.43) RAB9ASMN1; SMN2NPC1TSHRHRH3
SCHEMBL1416215 0.85 LMNA (0.44) RAB9ASMN1; SMN2NPC1TSHRHRH3
SCHEMBL1416094 0.83 L3MBTL1 (0.44) RAB9ASMN1; SMN2NPC1TSHRHRH3
SCHEMBL1416260 0.81 MMP3 (0.47) RAB9ASMN1; SMN2NPC1TSHRLMNA
SCHEMBL1416481 0.79 SMN1; SMN2 (0.59) RAB9ASMN1; SMN2NPC1
SCHEMBL4001304 0.76 MTNR1A (0.53) RAB9ASMN1; SMN2NPC1TSHRMEN1
SCHEMBL6103227 0.76 SMN1; SMN2 (0.51) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL1415807 0.75 SMN1; SMN2 (0.38) RAB9ASMN1; SMN2NPC1TSHRHRH3
SCHEMBL3154782 0.74 L3MBTL1 (0.70) RAB9ASMN1; SMN2NPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2165830-B1 Lithographic printing plate precursor and printing method using the same FUJIFILM CORP (JP) 2011-03-16 EP disclosed
US-20100071574-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
EP-2165830-A1 Lithographic printing plate precursor and printing method using the same Fujifilm Corporation (JP) 2010-03-24 EP disclosed