Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8610411 | 0.80 | KDM4E (0.35) | KDM4EGAALMNACYP1A2CYP3A4 | |
| SCHEMBL28533470 | 0.74 | GABRA1 (0.41) | KDM4EGAALMNACYP1A2CYP3A4 | |
| SCHEMBL3265467 | 0.72 | GAA (0.39) | KDM4EGAALMNACYP1A2CYP3A4 | |
| SCHEMBL83597 | 0.71 | GABRA1 (0.39) | KDM4EGAALMNACYP1A2CYP3A4 | |
| SCHEMBL18668719 | 0.71 | KMT2A (0.40) | KDM4EGAALMNACYP1A2CYP3A4 | |
| SCHEMBL9614876 | 0.71 | GABRA1 (0.39) | KDM4EGAALMNACYP1A2CYP3A4 | |
| SCHEMBL251314 | 0.70 | PTGDR2 (0.40) | KDM4EGAALMNACYP1A2CYP3A4 | |
| SCHEMBL8605584 | 0.70 | ADRA2B (0.36) | KDM4EGAALMNACYP1A2CYP3A4 | |
| SCHEMBL9570548 | 0.70 | ADRA1A (0.44) | HTR1AADRA2APRCP | |
| SCHEMBL173300 | 0.70 | GABRA1 (0.56) | KDM4ELMNACYP1A2CYP2D6GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594878-B1 | AVERMECTIN MONOSACCHARIDE DERIVATIVES HAVING PESTICIDAL PROPERTIES | MERIAL LTD (GB) | 2008-06-04 | — | — | EP | disclosed |