Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4386672 | 0.80 | NISCH (0.60) | ALDH1A1TDP1TSHRPKMLMNA | |
| SCHEMBL4395974 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRPKMLMNA | |
| SCHEMBL143761 | 0.76 | NISCH (0.41) | NISCHPOLBPARP1PARP10PARP11 | |
| SCHEMBL11847292 | 0.73 | ALDH1A1 (0.78) | ALDH1A1TDP1TSHRPKMLMNA | |
| SCHEMBL3535923 | 0.68 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRPKMLMNA | |
| SCHEMBL635089 | 0.67 | ALDH1A1 (1.00) | ALDH1A1TDP1TSHRLMNAHPGD | |
| SCHEMBL31546538 | 0.67 | ALDH1A1 (0.51) | ALDH1A1TDP1TSHRPKMLMNA | |
| SCHEMBL4389459 | 0.67 | ALDH1A1 (0.51) | ALDH1A1TDP1TSHRPKMLMNA | |
| SCHEMBL7814268 | 0.66 | ALDH1A1 (0.64) | ALDH1A1TDP1TSHRPKMLMNA | |
| SCHEMBL28521563 | 0.65 | ALDH1A1 (0.95) | ALDH1A1TDP1TSHRPKMLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926728-B1 | OXADIAZINE-SUBSTITUTED ARYLAMIDES | BAYER IP GMBH (DE) | 2017-04-05 | — | — | EP | disclosed |
| US-8486934-B2 | Oxadiazine-substituted arylamides | BAYER CROPSCIENCE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| US-20120058891-A1 | Oxadizine-Substituted Arylamides | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
| CN-101287731-B | Dioxazine-substituted arylamides and oxdiazine-substituted arylamides | BAYER CROPSCIENCE AG (DE) | 2012-02-08 | — | — | CN | disclosed |
| US-8062995-B2 | Dioxazine-substituted arylamides | BAYER CROPSCIENCE AG (DE) | 2011-11-22 | — | — | US | disclosed |
| US-20090143228-A1 | Dioxazine-and Oxadiazine-Substitude Arylamide | BAYER CROPSCIENCE AG (DE) | 2009-06-04 | — | — | US | disclosed |
| CN-101287731-A | Dioxazine- and oxdiazine-substituted arylamides | BAYER CROPSCIENCE AG (DE) | 2008-10-15 | — | — | CN | disclosed |
| EP-1926728-A1 | DIOXAZINE- AND OXADIAZINE-SUBSTITUTED ARYLAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007031213-A1 | DIOXAZINE- AND OXADIAZINE-SUBSTITUTED ARYLAMIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143228-A1 | Dioxazine-and Oxadiazine-Substitude Arylamide | PRXL2A, AOX1, DDT | ALDH1A1 105/4885TDP1 2298/4885TSHR 299/4885 |
| US-20120058891-A1 | Oxadizine-Substituted Arylamides | DDT, OXER1, PRXL2A | ALDH1A1 119/4885TDP1 2356/4885TSHR 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.