SCHEMBL2449865

SCHEMBL2449865

CCOCCOc1[c]cccc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.38
NCF1 P14598 4/20 0.38
ALDH1A1 P00352 3/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
THRA P10827 1/20 0.32
KDM4E B2RXH2 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4725404 0.91 SMN1; SMN2 (0.36) L3MBTL1NCF1ALDH1A1LMNAMAPT
SCHEMBL9668507 0.91 SMN1; SMN2 (0.36) L3MBTL1NCF1ALDH1A1LMNAMAPT
SCHEMBL7281298 0.87 L3MBTL1 (0.37) L3MBTL1ALDH1A1LMNAMAPTKMT2A
SCHEMBL6238419 0.86 JAK2 (0.33) ALDH1A1LMNAMAPTTAAR1KDM4E
SCHEMBL7157592 0.84 RARB (0.40) L3MBTL1ALDH1A1LMNAMEN1KMT2A
SCHEMBL7779040 0.84 L3MBTL1 (0.37) L3MBTL1ALDH1A1LMNAMAPTMEN1
SCHEMBL2499529 0.83 LTA4H (0.34) ALDH1A1
SCHEMBL126227 0.82 ALDH1A1 (0.34) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL49802 0.82
SCHEMBL49991 0.81 LTA4H (0.46) L3MBTL1ALDH1A1MAPTKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100317653-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS ASTRAZENECA AB (SE) 2010-12-16 US claimed
US-20080312271-A1 AZABENZIMIDAZOLYL COMPOUNDS PFIZER INC. 2008-12-18 US claimed
US-20080280933-A1 BENZIMIDAZOLYL COMPOUNDS EFREMOV IVAN 2008-11-13 US claimed
US-20080096874-A1 Oxadiazole Derivative as Dgat Inhibitors ASTRAZENECA AB (SE) 2008-04-24 US claimed
WO-2008012623-A1 BENZIMIDAZOLYL COMPOUNDS AS POTENTIATORS OF MGLUR2 SUBTYPE OF GLUTAMATE RECEPTOR PFIZER PRODUCTS INC. (US) 2008-01-31 WO claimed
WO-2008012622-A2 AZABENZIMIDAZOLYL COMPOUNDS AS POTENTIATORS OF MGLUR2 SUBTYPE OF GLUTAMATE RECEPTOR PFIZER PRODUCTS INC. (US) 2008-01-31 WO claimed
EP-1833806-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS AstraZeneca AB (SE) 2007-09-19 EP claimed
WO-2006064189-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS ASTRAZENECA AB (SE) 2006-06-22 WO claimed
US-11945152-B2 Model material ink set, support material composition, ink set, three-dimensional shaped object, and method for manufacturing three-dimensional shaped object MAXELL, LTD. (JP) 2024-04-02 US disclosed
CN-116981658-A Novel contrast agents for magnetic resonance imaging 拜耳股份有限公司 2023-10-31 CN disclosed
US-20230174806-A1 MODEL MATERIAL CLEAR COMPOSITION, MODEL MATERIAL COMPOSITION SET, AND COMPOSITION SET FOR OPTICAL SHAPING MAXELL, LTD. (JP) 2023-06-08 US disclosed
EP-3578338-B1 MODEL MATERIAL INK SET, SUPPORT MATERIAL COMPOSITION, INK SET, THREE-DIMENSIONAL SHAPED OBJECT, AND METHOD FOR MANUFACTURING THREE-DIMENSIONAL SHAPED OBJECT MAXELL LTD (JP) 2023-05-10 EP disclosed
US-20230100703-A1 MODEL MATERIAL CLEAR COMPOSITION AND COMPOSITION SET FOR OPTICAL SHAPING MAXELL, LTD. (JP) 2023-03-30 US disclosed
CN-110105316-B Resveratrol-phthalide hybrid compound and preparation method and application thereof 合肥工业大学 2022-10-21 CN disclosed
US-6337304-B1 HEAT EXCHANGING RECORDING IMAGE RECEIVERS AND DYES KONICA CORPORATION (JP) 2002-01-08 US disclosed
US-5847218-A Sulfonium salts and chemically amplified positive resist compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-12-08 US disclosed
US-5804102-A USE OF METAL COMPLEXES TO CUT OFF NEAR INFRARED RAYS; PREVENTION OF INTERFERENCE BETWEEN TELEVISION AND OTHER REMOTE CONTROLLED ELECTRONICS MITSUI CHEMICALS, INC. (JP) 1998-09-08 US disclosed
EP-0782164-A1 Plasma display filter MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1997-07-02 EP disclosed
EP-0190444-B1 OPTICAL-RECORDING MEDIUM BASF Aktiengesellschaft (DE) 1988-09-21 EP disclosed
EP-0190444-A1 Optical-recording medium BASF Aktiengesellschaft (DE) 1986-08-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317653-A1 OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS DGAT1, DGAT2, GPR119 L3MBTL1 1959/4885NCF1 3702/4885ALDH1A1 314/4885
US-20080280933-A1 BENZIMIDAZOLYL COMPOUNDS PAICS, TMBIM6, ABCG2 L3MBTL1 4582/4885NCF1 3079/4885ALDH1A1 260/4885
US-20080312271-A1 AZABENZIMIDAZOLYL COMPOUNDS AZI2, PAICS, UGT2B7 L3MBTL1 4740/4885NCF1 2323/4885ALDH1A1 394/4885
US-20080096874-A1 Oxadiazole Derivative as Dgat Inhibitors DGAT1, DGAT2, GPR119 L3MBTL1 2007/4885NCF1 3776/4885ALDH1A1 303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.