Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | HEXA | P06865 | 3/20 | 0.37 |
| ▸ | HEXB | P07686 | 3/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14165572 | 0.87 | KDM4E (0.45) | LMNAPKMHTTKMT2ARAB9A | |
| SCHEMBL14164947 | 0.84 | LMNA (0.44) | LMNAPKMHTTKMT2ARAB9A | |
| SCHEMBL4921134 | 0.83 | PDK2 (0.48) | LMNAPKMHTTKMT2ARAB9A | |
| SCHEMBL14165113 | 0.83 | MTNR1A (0.36) | KMT2AKDM4EPOLB | |
| SCHEMBL10031005 | 0.82 | KDM4E (0.47) | PKMHTTKMT2AL3MBTL1KDM4E | |
| SCHEMBL14172965 | 0.81 | PDK2 (0.40) | LMNAPKMHTTKMT2ARAB9A | |
| SCHEMBL4923313 | 0.81 | PDK2 (0.40) | LMNAPKMHTTKMT2ARAB9A | |
| SCHEMBL14165342 | 0.80 | KMT2A (0.44) | PKMHTTKMT2ARAB9ATDP1 | |
| SCHEMBL14165223 | 0.75 | KDM4E (0.38) | LMNAPKMKMT2ARAB9AHEXA | |
| SCHEMBL4928249 | 0.73 | HTT (0.58) | HTTKMT2ARAB9AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139493-A1 | Bi- or Tetra-Guanidino-Biphenyl Compounds as Small Molecule Carriers | UCL BUSINESS PLC (GB) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139493-A1 | Bi- or Tetra-Guanidino-Biphenyl Compounds as Small Molecule Carriers | CBR3, CBR1, KCNQ3 | LMNA 1393/4885PKM 4011/4885HTT 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.