Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14165113 | 0.85 | MTNR1A (0.36) | KDM4EALDH1A1MEN1KMT2AMTNR1A | |
| SCHEMBL14165191 | 0.82 | LMNA (0.42) | KDM4ESMN1; SMN2HTTL3MBTL1PKM | |
| SCHEMBL10031011 | 0.79 | F10 (0.48) | KDM4EADRB2ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL10064286 | 0.75 | PDK2 (0.45) | KDM4EALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL14165034 | 0.70 | KDM4E (0.34) | KDM4EADRB2ALDH1A1L3MBTL1MTNR1A | |
| SCHEMBL14669731 | 0.66 | MAPK1 (0.54) | KDM4EHTTL3MBTL1 | |
| SCHEMBL11023137 | 0.66 | PTPRC (0.44) | KDM4EADRB2L3MBTL1GAAMEN1 | |
| SCHEMBL12993182 | 0.66 | HTR1B (0.70) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL14165193 | 0.65 | F10 (0.41) | ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL11017667 | 0.65 | MAPK1 (0.49) | KDM4EADRB2L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077863-A1 | GUANIDINO-SUBSTITUTED BI-AND POLYPHENYLS AS SMALL MOLECULE CARRIERS | UCL BUSINESS PLC (GB) | 2012-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077863-A1 | GUANIDINO-SUBSTITUTED BI-AND POLYPHENYLS AS SMALL MOLECULE CARRIERS | CFTR, GNB1, GMPS | KDM4E 3544/4885ADRB2 180/4885ALDH1A1 3297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.