Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13793540 | 0.91 | ALDH1A1 (0.59) | POLBALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL14559816 | 0.90 | POLB (0.42) | POLBALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL14067812 | 0.81 | CHRNB2 (0.46) | POLBALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL8050961 | 0.81 | — | — | |
| SCHEMBL1416553 | 0.81 | — | — | |
| SCHEMBL14030899 | 0.79 | — | — | |
| SCHEMBL9921632 | 0.79 | — | — | |
| SCHEMBL15315487 | 0.79 | LMNA (0.56) | POLBALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL18288642 | 0.77 | POLB (0.57) | POLBALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL13793691 | 0.77 | NPC1 (0.45) | POLBALDH1A1KDM4ELMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879856-B1 | ALKYL-, ALKENYL- AND ALKYNYL CARBAMATE DERIVATIVES, THE PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2011-03-16 | — | — | EP | disclosed |
| EP-1879856-A2 | ALKYL-, ALKENYL- AND ALKYNYL CARBAMATE DERIVATIVES, THE PREPARATION AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117461-A2 | ALKYL-, ALKENYL- ET ALKYNYL CARBAMATE DERIVATIVES, THE PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2006-11-09 | — | — | WO | disclosed |
| US-6245465-B1 | ELECTROLYTES AND ELECTRIC CURRENTS WITH SULFONES | MOLTECH CORPORATION | 2001-06-12 | — | — | US | disclosed |
| WO-1999019932-A1 | NON-AQUEOUS ELECTROLYTE SOLVENTS FOR SECONDARY CELLS | MOLTECH CORPORATION (US) | 1999-04-22 | — | — | WO | disclosed |